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Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor.
Kim SH, Bajji A, Tangallapally R, Markovitz B, Trovato R, Shenderovich M, Baichwal V, Bartel P, Cimbora D, McKinnon R, Robinson R, Papac D, Wettstein D, Carlson R, Yager KM. Kim SH, et al. Among authors: bartel p. J Med Chem. 2012 Sep 13;55(17):7480-501. doi: 10.1021/jm3004619. Epub 2012 Aug 31. J Med Chem. 2012. PMID: 22913511
Characterization of a carboxy-terminal BRCA1 interacting protein.
Wong AK, Ormonde PA, Pero R, Chen Y, Lian L, Salada G, Berry S, Lawrence Q, Dayananth P, Ha P, Tavtigian SV, Teng DH, Bartel PL. Wong AK, et al. Among authors: bartel pl. Oncogene. 1998 Nov 5;17(18):2279-85. doi: 10.1038/sj.onc.1202150. Oncogene. 1998. PMID: 9811458
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.
Teng DH, Perry WL 3rd, Hogan JK, Baumgard M, Bell R, Berry S, Davis T, Frank D, Frye C, Hattier T, Hu R, Jammulapati S, Janecki T, Leavitt A, Mitchell JT, Pero R, Sexton D, Schroeder M, Su PH, Swedlund B, Kyriakis JM, Avruch J, Bartel P, Wong AK, Tavtigian SV, et al. Teng DH, et al. Among authors: bartel p. Cancer Res. 1997 Oct 1;57(19):4177-82. Cancer Res. 1997. PMID: 9331070
93 results