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Inclusion bodies are a site of ebolavirus replication.
Hoenen T, Shabman RS, Groseth A, Herwig A, Weber M, Schudt G, Dolnik O, Basler CF, Becker S, Feldmann H. Hoenen T, et al. Among authors: shabman rs. J Virol. 2012 Nov;86(21):11779-88. doi: 10.1128/JVI.01525-12. Epub 2012 Aug 22. J Virol. 2012. PMID: 22915810 Free PMC article.
An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, Amarasinghe GK. Leung DW, et al. Among authors: shabman rs. Cell Rep. 2015 Apr 21;11(3):376-89. doi: 10.1016/j.celrep.2015.03.034. Epub 2015 Apr 9. Cell Rep. 2015. PMID: 25865894 Free PMC article.
Filoviral immune evasion mechanisms.
Ramanan P, Shabman RS, Brown CS, Amarasinghe GK, Basler CF, Leung DW. Ramanan P, et al. Among authors: shabman rs. Viruses. 2011 Sep;3(9):1634-49. doi: 10.3390/v3091634. Epub 2011 Sep 7. Viruses. 2011. PMID: 21994800 Free PMC article. Review.
In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.
Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, Binning JM, Tonelli M, Olson MA, Davey RA, Ready JM, Basler CF, Amarasinghe GK. Brown CS, et al. Among authors: shabman rs. J Mol Biol. 2014 May 15;426(10):2045-58. doi: 10.1016/j.jmb.2014.01.010. Epub 2014 Feb 1. J Mol Biol. 2014. PMID: 24495995 Free PMC article.
49 results