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CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction.
Peretz Y, He Z, Shi Y, Yassine-Diab B, Goulet JP, Bordi R, Filali-Mouhim A, Loubert JB, El-Far M, Dupuy FP, Boulassel MR, Tremblay C, Routy JP, Bernard N, Balderas R, Haddad EK, Sékaly RP. Peretz Y, et al. Among authors: shi y. PLoS Pathog. 2012;8(8):e1002840. doi: 10.1371/journal.ppat.1002840. Epub 2012 Aug 16. PLoS Pathog. 2012. PMID: 22916009 Free PMC article. Clinical Trial.
Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.
Said EA, Dupuy FP, Trautmann L, Zhang Y, Shi Y, El-Far M, Hill BJ, Noto A, Ancuta P, Peretz Y, Fonseca SG, Van Grevenynghe J, Boulassel MR, Bruneau J, Shoukry NH, Routy JP, Douek DC, Haddad EK, Sekaly RP. Said EA, et al. Among authors: shi y. Nat Med. 2010 Apr;16(4):452-9. doi: 10.1038/nm.2106. Epub 2010 Mar 7. Nat Med. 2010. PMID: 20208540 Free PMC article.
Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection.
Trautmann L, Mbitikon-Kobo FM, Goulet JP, Peretz Y, Shi Y, Van Grevenynghe J, Procopio FA, Boulassel MR, Routy JP, Chomont N, Haddad EK, Sekaly RP. Trautmann L, et al. Among authors: shi y. Blood. 2012 Oct 25;120(17):3466-77. doi: 10.1182/blood-2012-04-422550. Epub 2012 Sep 6. Blood. 2012. PMID: 22955926 Free PMC article.
Generation and maintenance of human memory cells during viral infection.
Halwani R, Doroudchi M, Yassine-Diab B, Janbazian L, Shi Y, Said EA, Haddad EK, Sékaly RP. Halwani R, et al. Among authors: shi y. Springer Semin Immunopathol. 2006 Nov;28(3):197-208. doi: 10.1007/s00281-006-0027-2. Epub 2006 Sep 12. Springer Semin Immunopathol. 2006. PMID: 16967292 Review.
Cellular and molecular mechanisms of memory T-cell survival.
Tanel A, Fonseca SG, Yassine-Diab B, Bordi R, Zeidan J, Shi Y, Benne C, Sékaly RP. Tanel A, et al. Among authors: shi y. Expert Rev Vaccines. 2009 Mar;8(3):299-312. doi: 10.1586/14760584.8.3.299. Expert Rev Vaccines. 2009. PMID: 19249972 Free PMC article. Review.
Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.
van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, Boulassel MR, Routy JP, Haddad EK, Sekaly RP. van Grevenynghe J, et al. Among authors: shi y. Nat Med. 2008 Mar;14(3):266-74. doi: 10.1038/nm1728. Epub 2008 Mar 2. Nat Med. 2008. PMID: 18311149
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells.
Riou C, Yassine-Diab B, Van grevenynghe J, Somogyi R, Greller LD, Gagnon D, Gimmig S, Wilkinson P, Shi Y, Cameron MJ, Campos-Gonzalez R, Balderas RS, Kelvin D, Sekaly RP, Haddad EK. Riou C, et al. Among authors: shi y. J Exp Med. 2007 Jan 22;204(1):79-91. doi: 10.1084/jem.20061681. Epub 2006 Dec 26. J Exp Med. 2007. PMID: 17190839 Free PMC article.
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