Pear W - Search Results

1

Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1.

Fragoso R, Mao T, Wang S, Schaffert S, Gong X, Yue S, Luong R, Min H, Yashiro-Ohtani Y, Davis M, Pear W, Chen CZ. Fragoso R, et al. Among authors: pear w. PLoS Genet. 2012;8(8):e1002855. doi: 10.1371/journal.pgen.1002855. Epub 2012 Aug 9. PLoS Genet. 2012. PMID: 22916024 Free PMC article.

2

Notch regulation of early thymocyte development.

Yashiro-Ohtani Y, Ohtani T, Pear WS. Yashiro-Ohtani Y, et al. Semin Immunol. 2010 Oct;22(5):261-9. doi: 10.1016/j.smim.2010.04.015. Epub 2010 Jul 13. Semin Immunol. 2010. PMID: 20630772 Review.

3

Identifying direct Notch transcriptional targets using the GSI-washout assay.

Bailis W, Yashiro-Ohtani Y, Pear WS. Bailis W, et al. Among authors: pear ws. Methods Mol Biol. 2014;1187:247-54. doi: 10.1007/978-1-4939-1139-4_19. Methods Mol Biol. 2014. PMID: 25053495 Review.

4

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.

Kobayashi M, Nabinger SC, Bai Y, Yoshimoto M, Gao R, Chen S, Yao C, Dong Y, Zhang L, Rodriguez S, Yashiro-Ohtani Y, Pear WS, Carlesso N, Yoder MC, Kapur R, Kaplan MH, Daniel Lacorazza H, Zhang ZY, Liu Y. Kobayashi M, et al. Stem Cells. 2017 Apr;35(4):1053-1064. doi: 10.1002/stem.2559. Epub 2017 Jan 19. Stem Cells. 2017. PMID: 28009085 Free PMC article.

5

Notch directly regulates Gata3 expression during T helper 2 cell differentiation.

Fang TC, Yashiro-Ohtani Y, Del Bianco C, Knoblock DM, Blacklow SC, Pear WS. Fang TC, et al. Immunity. 2007 Jul;27(1):100-10. doi: 10.1016/j.immuni.2007.04.018. Epub 2007 Jul 19. Immunity. 2007. PMID: 17658278 Free PMC article.

6

The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

Maillard I, Tu L, Sambandam A, Yashiro-Ohtani Y, Millholland J, Keeshan K, Shestova O, Xu L, Bhandoola A, Pear WS. Maillard I, et al. J Exp Med. 2006 Oct 2;203(10):2239-45. doi: 10.1084/jem.20061020. Epub 2006 Sep 11. J Exp Med. 2006. PMID: 16966428 Free PMC article.

7

Notch1 co-opts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas.

Spaulding C, Reschly EJ, Zagort DE, Yashiro-Ohtani Y, Beverly LJ, Capobianco A, Pear WS, Kee BL. Spaulding C, et al. Blood. 2007 Oct 1;110(7):2650-8. doi: 10.1182/blood-2007-04-084202. Epub 2007 Jun 21. Blood. 2007. PMID: 17585052 Free article.

8

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.

Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS. Yashiro-Ohtani Y, et al. Among authors: pear ws. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):E4946-53. doi: 10.1073/pnas.1407079111. Epub 2014 Nov 4. Proc Natl Acad Sci U S A. 2014. PMID: 25369933 Free PMC article.

9

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals.

Bailis W, Yashiro-Ohtani Y, Fang TC, Hatton RD, Weaver CT, Artis D, Pear WS. Bailis W, et al. Among authors: pear ws. Immunity. 2013 Jul 25;39(1):148-59. doi: 10.1016/j.immuni.2013.07.006. Immunity. 2013. PMID: 23890069 Free PMC article.

10

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.

Weng AP, Millholland JM, Yashiro-Ohtani Y, Arcangeli ML, Lau A, Wai C, Del Bianco C, Rodriguez CG, Sai H, Tobias J, Li Y, Wolfe MS, Shachaf C, Felsher D, Blacklow SC, Pear WS, Aster JC. Weng AP, et al. Genes Dev. 2006 Aug 1;20(15):2096-109. doi: 10.1101/gad.1450406. Epub 2006 Jul 17. Genes Dev. 2006. PMID: 16847353 Free PMC article.

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