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The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy.
Tamouza H, Chemouny JM, Raskova Kafkova L, Berthelot L, Flamant M, Demion M, Mesnard L, Paubelle E, Walker F, Julian BA, Tissandié E, Tiwari MK, Camara NO, Vrtovsnik F, Benhamou M, Novak J, Monteiro RC, Moura IC. Tamouza H, et al. Among authors: benhamou m. Kidney Int. 2012 Dec;82(12):1284-96. doi: 10.1038/ki.2012.192. Epub 2012 Sep 5. Kidney Int. 2012. PMID: 22951891 Free PMC article.
Pathogenic significance of IgA receptor interactions in IgA nephropathy.
Monteiro RC, Moura IC, Launay P, Tsuge T, Haddad E, Benhamou M, Cooper MD, Arcos-Fajardo M. Monteiro RC, et al. Among authors: benhamou m. Trends Mol Med. 2002 Oct;8(10):464-8. doi: 10.1016/s1471-4914(02)02405-x. Trends Mol Med. 2002. PMID: 12383768 Review.
Engagement of transferrin receptor by polymeric IgA1: evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy.
Moura IC, Arcos-Fajardo M, Gdoura A, Leroy V, Sadaka C, Mahlaoui N, Lepelletier Y, Vrtovsnik F, Haddad E, Benhamou M, Monteiro RC. Moura IC, et al. Among authors: benhamou m. J Am Soc Nephrol. 2005 Sep;16(9):2667-76. doi: 10.1681/ASN.2004111006. Epub 2005 Jun 29. J Am Soc Nephrol. 2005. PMID: 15987753
180 results