Park EJ - Search Results

1

Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.

Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M. Lee JH, et al. Among authors: park hw, park ej, park hl. Cell Metab. 2012 Sep 5;16(3):311-21. doi: 10.1016/j.cmet.2012.08.004. Cell Metab. 2012. PMID: 22958918 Free PMC article.

2

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.

Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M. Lee JH, et al. Among authors: park ej. Science. 2010 Mar 5;327(5970):1223-8. doi: 10.1126/science.1182228. Science. 2010. PMID: 20203043 Free PMC article.

3

Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.

Umemura A, Park EJ, Taniguchi K, Lee JH, Shalapour S, Valasek MA, Aghajan M, Nakagawa H, Seki E, Hall MN, Karin M. Umemura A, et al. Among authors: park ej. Cell Metab. 2014 Jul 1;20(1):133-44. doi: 10.1016/j.cmet.2014.05.001. Epub 2014 Jun 5. Cell Metab. 2014. PMID: 24910242 Free PMC article.

4

Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.

Holzer RG, Park EJ, Li N, Tran H, Chen M, Choi C, Solinas G, Karin M. Holzer RG, et al. Among authors: park ej. Cell. 2011 Sep 30;147(1):173-84. doi: 10.1016/j.cell.2011.08.034. Cell. 2011. PMID: 21962514 Free PMC article.

5

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression.

Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, Osterreicher CH, Takahashi H, Karin M. Park EJ, et al. Cell. 2010 Jan 22;140(2):197-208. doi: 10.1016/j.cell.2009.12.052. Cell. 2010. PMID: 20141834 Free PMC article.

6

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis.

Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E. Inokuchi-Shimizu S, et al. Among authors: park ej. J Clin Invest. 2014 Aug;124(8):3566-78. doi: 10.1172/JCI74068. Epub 2014 Jul 1. J Clin Invest. 2014. PMID: 24983318 Free PMC article.

7

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.

Li N, Wu X, Holzer RG, Lee JH, Todoric J, Park EJ, Ogata H, Gukovskaya AS, Gukovsky I, Pizzo DP, VandenBerg S, Tarin D, Atay C, Arkan MC, Deerinck TJ, Moscat J, Diaz-Meco M, Dawson D, Erkan M, Kleeff J, Karin M. Li N, et al. Among authors: park ej. J Clin Invest. 2013 May;123(5):2231-43. doi: 10.1172/JCI64498. Epub 2013 Apr 8. J Clin Invest. 2013. PMID: 23563314 Free PMC article.

8

Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage.

Ali SR, Timmer AM, Bilgrami S, Park EJ, Eckmann L, Nizet V, Karin M. Ali SR, et al. Among authors: park ej. Immunity. 2011 Jul 22;35(1):34-44. doi: 10.1016/j.immuni.2011.04.015. Epub 2011 Jun 16. Immunity. 2011. PMID: 21683629 Free PMC article.

9

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse.

Moles A, Murphy L, Wilson CL, Chakraborty JB, Fox C, Park EJ, Mann J, Oakley F, Howarth R, Brain J, Masson S, Karin M, Seki E, Mann DA. Moles A, et al. Among authors: park ej. J Hepatol. 2014 Apr;60(4):782-91. doi: 10.1016/j.jhep.2013.12.005. Epub 2013 Dec 11. J Hepatol. 2014. PMID: 24333183 Free PMC article.

10

Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice.

Inokuchi S, Tsukamoto H, Park E, Liu ZX, Brenner DA, Seki E. Inokuchi S, et al. Alcohol Clin Exp Res. 2011 Aug;35(8):1509-18. doi: 10.1111/j.1530-0277.2011.01487.x. Epub 2011 Apr 4. Alcohol Clin Exp Res. 2011. PMID: 21463341 Free PMC article.

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