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Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone.
Zheng Y, Yang J, Qian J, Zhang L, Lu Y, Li H, Lin H, Lan Y, Liu Z, He J, Hong S, Thomas S, Shah J, Baladandayuthapani V, Kwak LW, Yi Q. Zheng Y, et al. Among authors: he j. J Mol Med (Berl). 2012 Jun;90(6):695-706. doi: 10.1007/s00109-011-0849-9. Epub 2011 Dec 30. J Mol Med (Berl). 2012. PMID: 22207485 Free PMC article.
Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.
Liu H, He J, Koh SP, Zhong Y, Liu Z, Wang Z, Zhang Y, Li Z, Tam BT, Lin P, Xiao M, Young KH, Amini B, Starbuck MW, Lee HC, Navone NM, Davis RE, Tong Q, Bergsagel PL, Hou J, Yi Q, Orlowski RZ, Gagel RF, Yang J. Liu H, et al. Among authors: he j. Sci Transl Med. 2019 May 29;11(494):eaau9087. doi: 10.1126/scitranslmed.aau9087. Sci Transl Med. 2019. PMID: 31142679 Free PMC article.
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