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Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels.
Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, Uhr M, Dose T, Unschuld PG, Zihl J, Binder E, Müller-Myhsok B, Holsboer F, Lucae S. Kloiber S, et al. Among authors: bruckl t. Eur Neuropsychopharmacol. 2013 Jul;23(7):653-62. doi: 10.1016/j.euroneuro.2012.08.010. Epub 2012 Sep 29. Eur Neuropsychopharmacol. 2013. PMID: 23026132 Free PMC article.
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, Kern N, Brunner J, Modell S, Baghai T, Deiml T, Zill P, Bondy B, Rupprecht R, Messer T, Köhnlein O, Dabitz H, Brückl T, Müller N, Pfister H, Lieb R, Mueller JC, Lõhmussaar E, Strom TM, Bettecken T, Meitinger T, Uhr M, Rein T, Holsboer F, Muller-Myhsok B. Binder EB, et al. Among authors: bruckl t. Nat Genet. 2004 Dec;36(12):1319-25. doi: 10.1038/ng1479. Epub 2004 Nov 21. Nat Genet. 2004. PMID: 15565110
Somatization in major depression--clinical features and genetic associations.
Klengel T, Heck A, Pfister H, Brückl T, Hennings JM, Menke A, Czamara D, Müller-Myhsok B, Ising M. Klengel T, et al. Among authors: bruckl t. Acta Psychiatr Scand. 2011 Oct;124(4):317-28. doi: 10.1111/j.1600-0447.2011.01743.x. Epub 2011 Aug 13. Acta Psychiatr Scand. 2011. PMID: 21838737
Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach.
Hennings JM, Kohli MA, Czamara D, Giese M, Eckert A, Wolf C, Heck A, Domschke K, Arolt V, Baune BT, Horstmann S, Brückl T, Klengel T, Menke A, Müller-Myhsok B, Ising M, Uhr M, Lucae S. Hennings JM, et al. Among authors: bruckl t. PLoS One. 2013 Jun 4;8(6):e64947. doi: 10.1371/journal.pone.0064947. Print 2013. PLoS One. 2013. PMID: 23750220 Free PMC article.
Functional coding variants in SLC6A15, a possible risk gene for major depression.
Quast C, Cuboni S, Bader D, Altmann A, Weber P, Arloth J, Röh S, Brückl T, Ising M, Kopczak A, Erhardt A, Hausch F, Lucae S, Binder EB. Quast C, et al. Among authors: bruckl t. PLoS One. 2013 Jul 16;8(7):e68645. doi: 10.1371/journal.pone.0068645. Print 2013. PLoS One. 2013. PMID: 23874702 Free PMC article.
62 results