Boussiotis VA - Search Results

1

PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A.

Patsoukis N, Sari D, Boussiotis VA. Patsoukis N, et al. Among authors: boussiotis va. Cell Cycle. 2012 Dec 1;11(23):4305-9. doi: 10.4161/cc.22135. Epub 2012 Oct 3. Cell Cycle. 2012. PMID: 23032366 Free PMC article.

2

CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression.

Appleman LJ, Berezovskaya A, Grass I, Boussiotis VA. Appleman LJ, et al. Among authors: boussiotis va. J Immunol. 2000 Jan 1;164(1):144-51. doi: 10.4049/jimmunol.164.1.144. J Immunol. 2000. PMID: 10605005

3

PD-L2 is a second ligand for PD-1 and inhibits T cell activation.

Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. Latchman Y, et al. Among authors: boussiotis va. Nat Immunol. 2001 Mar;2(3):261-8. doi: 10.1038/85330. Nat Immunol. 2001. PMID: 11224527

4

Helper T cell anergy: from biochemistry to cancer pathophysiology and therapeutics.

Appleman LJ, Tzachanis D, Grader-Beck T, van Puijenbroek AA, Boussiotis VA. Appleman LJ, et al. Among authors: boussiotis va. J Mol Med (Berl). 2001;78(12):673-83. doi: 10.1007/s001090000180. J Mol Med (Berl). 2001. PMID: 11434720 Review.

5

Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).

Barata JT, Cardoso AA, Nadler LM, Boussiotis VA. Barata JT, et al. Among authors: boussiotis va. Blood. 2001 Sep 1;98(5):1524-31. doi: 10.1182/blood.v98.5.1524. Blood. 2001. PMID: 11520803 Free article.

6

CTLA-4 regulates cell cycle progression during a primary immune response.

Greenwald RJ, Oosterwegel MA, van der Woude D, Kubal A, Mandelbrot DA, Boussiotis VA, Sharpe AH. Greenwald RJ, et al. Among authors: boussiotis va. Eur J Immunol. 2002 Feb;32(2):366-73. doi: 10.1002/1521-4141(200202)32:2<366::AID-IMMU366>3.0.CO;2-5. Eur J Immunol. 2002. PMID: 11807776 Free article.

7

CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells.

Appleman LJ, van Puijenbroek AA, Shu KM, Nadler LM, Boussiotis VA. Appleman LJ, et al. Among authors: boussiotis va. J Immunol. 2002 Mar 15;168(6):2729-36. doi: 10.4049/jimmunol.168.6.2729. J Immunol. 2002. PMID: 11884439

8

cAMP inhibits both Ras and Rap1 activation in primary human T lymphocytes, but only Ras inhibition correlates with blockade of cell cycle progression.

Grader-Beck T, van Puijenbroek AA, Nadler LM, Boussiotis VA. Grader-Beck T, et al. Among authors: boussiotis va. Blood. 2003 Feb 1;101(3):998-1006. doi: 10.1182/blood-2002-06-1665. Epub 2002 Sep 19. Blood. 2003. PMID: 12393539 Free article.

9

IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL.

Barata JT, Boussiotis VA, Yunes JA, Ferrando AA, Moreau LA, Veiga JP, Sallan SE, Look AT, Nadler LM, Cardoso AA. Barata JT, et al. Among authors: boussiotis va. Blood. 2004 Mar 1;103(5):1891-900. doi: 10.1182/blood-2002-12-3861. Epub 2003 Nov 13. Blood. 2004. PMID: 14615384 Free article.

10

CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.

Appleman LJ, Chernova I, Li L, Boussiotis VA. Appleman LJ, et al. Among authors: boussiotis va. Cell Cycle. 2006 Sep;5(18):2123-9. doi: 10.4161/cc.5.18.3139. Epub 2006 Sep 15. Cell Cycle. 2006. PMID: 16969077

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