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Pharmacokinetic optimization of class-selective histone deacetylase inhibitors and identification of associated candidate predictive biomarkers of hepatocellular carcinoma tumor response.
Wong JC, Tang G, Wu X, Liang C, Zhang Z, Guo L, Peng Z, Zhang W, Lin X, Wang Z, Mei J, Chen J, Pan S, Zhang N, Liu Y, Zhou M, Feng L, Zhao W, Li S, Zhang C, Zhang M, Rong Y, Jin TG, Zhang X, Ren S, Ji Y, Zhao R, She J, Ren Y, Xu C, Chen D, Cai J, Shan S, Pan D, Ning Z, Lu X, Chen T, He Y, Chen L. Wong JC, et al. Among authors: zhang n, zhang m, zhang c, zhang w, zhang z, zhang x. J Med Chem. 2012 Oct 25;55(20):8903-25. doi: 10.1021/jm3011838. Epub 2012 Oct 12. J Med Chem. 2012. PMID: 23061376
Application of p21 and klf2 reporter gene assays to identify selective histone deacetylase inhibitors for cancer therapy.
Wong JC, Guo L, Peng Z, Zhang W, Zhang N, Lai W, Zhang Z, Zhang C, Zhang X, Song S, Pan D, Xie C, Li J, Ning Z, Lu X, He Y, Chen L. Wong JC, et al. Among authors: zhang n, zhang c, zhang w, zhang z, zhang x. Bioorg Med Chem Lett. 2011 Jan 1;21(1):110-6. doi: 10.1016/j.bmcl.2010.11.063. Epub 2010 Nov 19. Bioorg Med Chem Lett. 2011. PMID: 21145737
Identification of a novel aminotetralin class of HDAC6 and HDAC8 selective inhibitors.
Tang G, Wong JC, Zhang W, Wang Z, Zhang N, Peng Z, Zhang Z, Rong Y, Li S, Zhang M, Yu L, Feng T, Zhang X, Wu X, Wu JZ, Chen L. Tang G, et al. Among authors: zhang n, zhang m, zhang w, zhang z, zhang x. J Med Chem. 2014 Oct 9;57(19):8026-34. doi: 10.1021/jm5008962. Epub 2014 Sep 30. J Med Chem. 2014. PMID: 25238284
19,282 results
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