Klos A - Search Results

1

Phosphorylation of C3a receptor at multiple sites mediates desensitization, β-arrestin-2 recruitment and inhibition of NF-κB activity in mast cells.

Gupta K, Subramanian H, Klos A, Ali H. Gupta K, et al. Among authors: klos a. PLoS One. 2012;7(10):e46369. doi: 10.1371/journal.pone.0046369. Epub 2012 Oct 15. PLoS One. 2012. PMID: 23077507 Free PMC article.

2

The complement anaphylatoxin C3a receptor (C3aR) contributes to the inflammatory response in dextran sulfate sodium (DSS)-induced colitis in mice.

Wende E, Laudeley R, Bleich A, Bleich E, Wetsel RA, Glage S, Klos A. Wende E, et al. Among authors: klos a. PLoS One. 2013 Apr 26;8(4):e62257. doi: 10.1371/journal.pone.0062257. Print 2013. PLoS One. 2013. PMID: 23638016 Free PMC article.

3

A recombinant hybrid anaphylatoxin with dual C3a/C5a activity.

Bautsch W, Kretzschmar T, Stühmer T, Kola A, Emde M, Köhl J, Klos A, Bitter-Suermann D. Bautsch W, et al. Among authors: klos a. Biochem J. 1992 Nov 15;288 ( Pt 1)(Pt 1):261-6. doi: 10.1042/bj2880261. Biochem J. 1992. PMID: 1445269 Free PMC article.

4

Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells.

Crass T, Raffetseder U, Martin U, Grove M, Klos A, Köhl J, Bautsch W. Crass T, et al. Among authors: klos a. Eur J Immunol. 1996 Aug;26(8):1944-50. doi: 10.1002/eji.1830260840. Eur J Immunol. 1996. PMID: 8765043

5

Site-directed C3a receptor antibodies from phage display libraries.

Hawlisch H, Frank R, Hennecke M, Baensch M, Sohns B, Arseniev L, Bautsch W, Kola A, Klos A, Köhl J. Hawlisch H, et al. Among authors: klos a. J Immunol. 1998 Mar 15;160(6):2947-58. J Immunol. 1998. PMID: 9510199

6

C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment.

Croker DE, Halai R, Kaeslin G, Wende E, Fehlhaber B, Klos A, Monk PN, Cooper MA. Croker DE, et al. Among authors: klos a. Immunol Cell Biol. 2014 Aug;92(7):631-9. doi: 10.1038/icb.2014.32. Epub 2014 Apr 29. Immunol Cell Biol. 2014. PMID: 24777312 Free article.

7

The transcription factors AP-1 and Ets are regulators of C3a receptor expression.

Schaefer M, Konrad S, Thalmann J, Rheinheimer C, Johswich K, Sohns B, Klos A. Schaefer M, et al. Among authors: klos a. J Biol Chem. 2005 Dec 23;280(51):42113-23. doi: 10.1074/jbc.M508146200. Epub 2005 Oct 27. J Biol Chem. 2005. PMID: 16253992 Free article.

8

Modulation of C3a activity: internalization of the human C3a receptor and its inhibition by C5a.

Settmacher B, Bock D, Saad H, Gärtner S, Rheinheimer C, Köhl J, Bautsch W, Klos A. Settmacher B, et al. Among authors: klos a. J Immunol. 1999 Jun 15;162(12):7409-16. J Immunol. 1999. PMID: 10358194

9

Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models.

Ames RS, Lee D, Foley JJ, Jurewicz AJ, Tornetta MA, Bautsch W, Settmacher B, Klos A, Erhard KF, Cousins RD, Sulpizio AC, Hieble JP, McCafferty G, Ward KW, Adams JL, Bondinell WE, Underwood DC, Osborn RR, Badger AM, Sarau HM. Ames RS, et al. Among authors: klos a. J Immunol. 2001 May 15;166(10):6341-8. doi: 10.4049/jimmunol.166.10.6341. J Immunol. 2001. PMID: 11342658

10

Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease.

Johswich K, Martin M, Bleich A, Kracht M, Dittrich-Breiholz O, Gessner JE, Suerbaum S, Wende E, Rheinheimer C, Klos A. Johswich K, et al. Among authors: klos a. Inflamm Bowel Dis. 2009 Dec;15(12):1812-23. doi: 10.1002/ibd.21012. Epub 2009 Aug 27. Inflamm Bowel Dis. 2009. PMID: 19714742

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