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Page 1
An engineered cereblon optimized for high throughput screening and molecular glue discovery.
Bailey HJ, Eisert J, Kazi R, Gerhartz J, Pieńkowska DE, Dressel I, Vollrath J, Kondratov I, Matviyuk T, Tolmachova N, Shah VJ, Giuliani G, Mosler T, Geiger TM, Esteves AM, Santos SP, Sousa RL, Bandeiras TM, Leibrock EM, Bauer U, Leuthner B, Langer JD, Wegener AA, Nowak RP, Sorrell FJ, Dikic I. Bailey HJ, et al. Among authors: giuliani g. Cell Chem Biol. 2024 Nov 20:S2451-9456(24)00460-4. doi: 10.1016/j.chembiol.2024.11.002. Online ahead of print. Cell Chem Biol. 2024. PMID: 39610248 Free article.
Use of imidazo[1,5-a]quinoline scaffold as the pharmacophore in the design of bivalent ligands of central benzodiazepine receptors.
Paolino M, Saletti M, Venditti J, Castriconi F, Giuliani G, Maramai S, Toti A, Ghelardini C, Matucci R, Villalobos NA, Anzini M, Cappelli A. Paolino M, et al. Among authors: giuliani g. Bioorg Med Chem. 2025 Jan 1;117:118006. doi: 10.1016/j.bmc.2024.118006. Epub 2024 Nov 14. Bioorg Med Chem. 2025. PMID: 39577296 Free article.
Enhancing cell motility via non-contact capacitively coupled electrostatic field.
Zironi I, Cramer T, Fuschi A, Cioni M, Guerra G, Giuliani G, Calienni M, Caramazza L, Liberti M, Apollonio F, Remondini D, Castellani G. Zironi I, et al. Among authors: giuliani g. Sci Rep. 2024 Nov 15;14(1):28085. doi: 10.1038/s41598-024-77384-9. Sci Rep. 2024. PMID: 39543219 Free PMC article.
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy.
Prieto-Garcia C, Matkovic V, Mosler T, Li C, Liang J, Oo JA, Haidle F, Mačinković I, Cabrera-Orefice A, Berkane R, Giuliani G, Xu F, Jacomin AC, Tomaskovic I, Basoglu M, Hoffmann ME, Rathore R, Cetin R, Boutguetait D, Bozkurt S, Hernández Cañás MC, Keller M, Busam J, Shah VJ, Wittig I, Kaulich M, Beli P, Galej WP, Ebersberger I, Wang L, Münch C, Stolz A, Brandes RP, Tse WKF, Eimer S, Stainier DYR, Legewie S, Zarnack K, Müller-McNicoll M, Dikic I. Prieto-Garcia C, et al. Among authors: giuliani g. Science. 2024 Nov 15;386(6723):768-776. doi: 10.1126/science.adi5295. Epub 2024 Nov 14. Science. 2024. PMID: 39541449
609 results