Eacho P - Search Results

1

Quantitative characterization of the mechanism of action and impact of a 'proteolysis-permitting' anti-PCSK9 antibody.

Hansen RJ, Berna MJ, Sperry AE, Beyer TP, Wroblewski VJ, Schroeder KM, Eacho PI. Hansen RJ, et al. Among authors: eacho pi. MAbs. 2017 Feb/Mar;9(2):285-296. doi: 10.1080/19420862.2016.1270490. MAbs. 2017. PMID: 27981884 Free PMC article.

2

Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody.

Schroeder KM, Beyer TP, Hansen RJ, Han B, Pickard RT, Wroblewski VJ, Kowala MC, Eacho PI. Schroeder KM, et al. Among authors: eacho pi. J Lipid Res. 2015 Nov;56(11):2124-32. doi: 10.1194/jlr.M061903. Epub 2015 Sep 20. J Lipid Res. 2015. PMID: 26392590 Free PMC article.

3

Isolation and characterization of the circulating truncated form of PCSK9.

Han B, Eacho PI, Knierman MD, Troutt JS, Konrad RJ, Yu X, Schroeder KM. Han B, et al. Among authors: eacho pi. J Lipid Res. 2014 Jul;55(7):1505-14. doi: 10.1194/jlr.M049346. Epub 2014 Apr 28. J Lipid Res. 2014. PMID: 24776539 Free PMC article.

4

Endothelial lipase activity predicts high-density lipoprotein catabolism in hemodialysis: novel phospholipase assay in postheparin human plasma.

Miksztowicz V, McCoy MG, Schreier L, Cacciagiú L, Elbert A, Gonzalez AI, Billheimer J, Eacho P, Rader DJ, Berg G. Miksztowicz V, et al. Among authors: eacho p. Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):3033-40. doi: 10.1161/ATVBAHA.112.300110. Epub 2012 Oct 25. Arterioscler Thromb Vasc Biol. 2012. PMID: 23104846

5

Varespladib (A-002), a secretory phospholipase A2 inhibitor, reduces atherosclerosis and aneurysm formation in ApoE-/- mice.

Fraser H, Hislop C, Christie RM, Rick HL, Reidy CA, Chouinard ML, Eacho PI, Gould KE, Trias J. Fraser H, et al. Among authors: eacho pi. J Cardiovasc Pharmacol. 2009 Jan;53(1):60-5. doi: 10.1097/FJC.0b013e318195bfbc. J Cardiovasc Pharmacol. 2009. PMID: 19129734

6

Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis.

Qian YW, Schmidt RJ, Zhang Y, Chu S, Lin A, Wang H, Wang X, Beyer TP, Bensch WR, Li W, Ehsani ME, Lu D, Konrad RJ, Eacho PI, Moller DE, Karathanasis SK, Cao G. Qian YW, et al. Among authors: eacho pi. J Lipid Res. 2007 Jul;48(7):1488-98. doi: 10.1194/jlr.M700071-JLR200. Epub 2007 Apr 20. J Lipid Res. 2007. PMID: 17449864 Free article.

7

A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity.

Schmidt RJ, Ficorilli JV, Zhang Y, Bramlett KS, Beyer TP, Borchert K, Dowless MS, Houck KA, Burris TP, Eacho PI, Liang G, Guo LW, Wilson WK, Michael LF, Cao G. Schmidt RJ, et al. Among authors: eacho pi. J Lipid Res. 2006 May;47(5):1037-44. doi: 10.1194/jlr.M500526-JLR200. Epub 2006 Jan 13. J Lipid Res. 2006. PMID: 16415294 Free article.

8

Hepatic peroxisomal fatty acid beta-oxidation is regulated by liver X receptor alpha.

Hu T, Foxworthy P, Siesky A, Ficorilli JV, Gao H, Li S, Christe M, Ryan T, Cao G, Eacho P, Michael MD, Michael LF. Hu T, et al. Among authors: eacho p. Endocrinology. 2005 Dec;146(12):5380-7. doi: 10.1210/en.2005-0591. Epub 2005 Aug 25. Endocrinology. 2005. PMID: 16123164

9

Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.

Köster A, Chao YB, Mosior M, Ford A, Gonzalez-DeWhitt PA, Hale JE, Li D, Qiu Y, Fraser CC, Yang DD, Heuer JG, Jaskunas SR, Eacho P. Köster A, et al. Among authors: eacho p. Endocrinology. 2005 Nov;146(11):4943-50. doi: 10.1210/en.2005-0476. Epub 2005 Aug 4. Endocrinology. 2005. PMID: 16081640

10

Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A.

Zhang Y, Schmidt RJ, Foxworthy P, Emkey R, Oler JK, Large TH, Wang H, Su EW, Mosior MK, Eacho PI, Cao G. Zhang Y, et al. Among authors: eacho pi. Biochem Biophys Res Commun. 2005 Aug 26;334(2):729-32. doi: 10.1016/j.bbrc.2005.06.141. Biochem Biophys Res Commun. 2005. PMID: 16018973

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