Skeldal S - Search Results

1

Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosis.

Skeldal S, Sykes AM, Glerup S, Matusica D, Palstra N, Autio H, Boskovic Z, Madsen P, Castrén E, Nykjaer A, Coulson EJ. Skeldal S, et al. J Biol Chem. 2012 Dec 21;287(52):43798-809. doi: 10.1074/jbc.M112.374710. Epub 2012 Oct 26. J Biol Chem. 2012. PMID: 23105113 Free PMC article.

2

Identification of a linear epitope in sortilin that partakes in pro-neurotrophin binding.

Serup Andersen O, Boisguerin P, Glerup S, Skeldal S, Volkmer R, Willnow TE, Nykjaer A, Andersen OM. Serup Andersen O, et al. Among authors: skeldal s. J Biol Chem. 2010 Apr 16;285(16):12210-22. doi: 10.1074/jbc.M109.062364. Epub 2010 Feb 16. J Biol Chem. 2010. PMID: 20159974 Free PMC article.

3

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.

Vaegter CB, Jansen P, Fjorback AW, Glerup S, Skeldal S, Kjolby M, Richner M, Erdmann B, Nyengaard JR, Tessarollo L, Lewin GR, Willnow TE, Chao MV, Nykjaer A. Vaegter CB, et al. Among authors: skeldal s. Nat Neurosci. 2011 Jan;14(1):54-61. doi: 10.1038/nn.2689. Epub 2010 Nov 21. Nat Neurosci. 2011. PMID: 21102451 Free PMC article.

4

Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR).

Skeldal S, Matusica D, Nykjaer A, Coulson EJ. Skeldal S, et al. Bioessays. 2011 Aug;33(8):614-25. doi: 10.1002/bies.201100036. Epub 2011 Jun 30. Bioessays. 2011. PMID: 21717487 Review.

5

The effects of transmembrane sequence and dimerization on cleavage of the p75 neurotrophin receptor by γ-secretase.

Sykes AM, Palstra N, Abankwa D, Hill JM, Skeldal S, Matusica D, Venkatraman P, Hancock JF, Coulson EJ. Sykes AM, et al. Among authors: skeldal s. J Biol Chem. 2012 Dec 21;287(52):43810-24. doi: 10.1074/jbc.M112.382903. Epub 2012 Oct 26. J Biol Chem. 2012. PMID: 23105112 Free PMC article.

6

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM. Ghai R, et al. Among authors: skeldal s. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52. doi: 10.1073/pnas.1216229110. Epub 2013 Feb 4. Proc Natl Acad Sci U S A. 2013. PMID: 23382219 Free PMC article.

7

An intracellular domain fragment of the p75 neurotrophin receptor (p75(NTR)) enhances tropomyosin receptor kinase A (TrkA) receptor function.

Matusica D, Skeldal S, Sykes AM, Palstra N, Sharma A, Coulson EJ. Matusica D, et al. Among authors: skeldal s. J Biol Chem. 2013 Apr 19;288(16):11144-54. doi: 10.1074/jbc.M112.436469. Epub 2013 Mar 7. J Biol Chem. 2013. PMID: 23471969 Free PMC article.

8

SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.

Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A. Glerup S, et al. Among authors: skeldal s. Neuron. 2014 Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022. Neuron. 2014. PMID: 24908487 Free article.

9

Inhibition of motor neuron death in vitro and in vivo by a p75 neurotrophin receptor intracellular domain fragment.

Matusica D, Alfonsi F, Turner BJ, Butler TJ, Shepheard SR, Rogers ML, Skeldal S, Underwood CK, Mangelsdorf M, Coulson EJ. Matusica D, et al. Among authors: skeldal s. J Cell Sci. 2016 Feb 1;129(3):517-30. doi: 10.1242/jcs.173864. Epub 2015 Oct 26. J Cell Sci. 2016. PMID: 26503157

10

Exploring the sortilin related receptor, SorLA, in depression.

Buttenschøn HN, Elfving B, Nielsen M, Skeldal S, Kaas M, Mors O, Glerup S. Buttenschøn HN, et al. Among authors: skeldal s. J Affect Disord. 2018 May;232:260-267. doi: 10.1016/j.jad.2018.02.050. Epub 2018 Feb 21. J Affect Disord. 2018. PMID: 29499509

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