Qian Y - Search Results

1

Characterization and identification of alanine to serine sequence variants in an IgG4 monoclonal antibody produced in mammalian cell lines.

Fu J, Bongers J, Tao L, Huang D, Ludwig R, Huang Y, Qian Y, Basch J, Goldstein J, Krishnan R, You L, Li ZJ, Russell RJ. Fu J, et al. Among authors: qian y. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Nov 1;908:1-8. doi: 10.1016/j.jchromb.2012.09.023. Epub 2012 Sep 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 23122394

2

Early identification of unusually clustered mutations and root causes in therapeutic antibody development.

Qian Y, Chen Z, Huang X, Wang X, Xu X, Kirov S, Ludwig R, Qian NX, Ravi K, Tao L, Borys MC, Li ZJ. Qian Y, et al. Among authors: qian nx. Biotechnol Bioeng. 2018 Sep;115(9):2377-2382. doi: 10.1002/bit.26728. Epub 2018 Jun 6. Biotechnol Bioeng. 2018. PMID: 29777592

3

Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics.

Chen Z, Qian Y, Song Y, Xu X, Tao L, Mussa N, Ghose S, Li ZJ. Chen Z, et al. Among authors: qian y. MAbs. 2020 Jan-Dec;12(1):1829338. doi: 10.1080/19420862.2020.1829338. MAbs. 2020. PMID: 33044887 Free PMC article.

4

Sialylation enhancement of CTLA4-Ig fusion protein in Chinese hamster ovary cells by dexamethasone.

Jing Y, Qian Y, Li ZJ. Jing Y, et al. Among authors: qian y. Biotechnol Bioeng. 2010 Oct 15;107(3):488-96. doi: 10.1002/bit.22827. Biotechnol Bioeng. 2010. PMID: 20521303

5

Glucocorticoid receptor-mediated reduction of IgG-fusion protein aggregation in Chinese hamster ovary cells.

Qian Y, Jing Y, Li ZJ. Qian Y, et al. Biotechnol Prog. 2010 Sep-Oct;26(5):1417-23. doi: 10.1002/btpr.456. Biotechnol Prog. 2010. PMID: 20549677

6

WITHDRAWN: Aminoglycoside phosphotransferase II gene as primary selection marker for Pichia pastoris producing full-length monoclonal antibody.

Qian Y, Xu X, Qian NX, Dhar V, You L, Xing Z, Huang C, Pan SH, Li ZJ. Qian Y, et al. Among authors: qian nx. Protein Expr Purif. 2012 Sep 5:S1046-5928(12)00238-0. doi: 10.1016/j.pep.2012.08.019. Online ahead of print. Protein Expr Purif. 2012. PMID: 22982086

7

Reduction of N-terminal methionylation while increasing titer by lowering metabolic and protein production rates in E. coli auto-induced fed-batch fermentation.

Xu J, Qian Y, Skonezny PM, You L, Xing Z, Meyers DS, Stankavage RJ, Pan SH, Li ZJ. Xu J, et al. Among authors: qian y. J Ind Microbiol Biotechnol. 2012 Aug;39(8):1199-208. doi: 10.1007/s10295-012-1127-8. Epub 2012 Apr 20. J Ind Microbiol Biotechnol. 2012. PMID: 22526331

8

Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines.

Tian J, He Q, Oliveira C, Qian Y, Egan S, Xu J, Qian NX, Langsdorf E, Warrack B, Aranibar N, Reily M, Borys M, Li ZJ. Tian J, et al. Among authors: qian nx, qian y. Eng Life Sci. 2020 Jan 9;20(3-4):112-125. doi: 10.1002/elsc.201900124. eCollection 2020 Mar. Eng Life Sci. 2020. PMID: 32874175 Free PMC article.

9

Computational insights into O-glycosylation in a CTLA4 Fc-fusion protein linker and its impact on protein quality attributes.

Song Y, Qian Y, Huang Z, Khattak SF, Li ZJ. Song Y, et al. Among authors: qian y. Comput Struct Biotechnol J. 2020 Dec 1;18:3925-3935. doi: 10.1016/j.csbj.2020.11.037. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 33335689 Free PMC article.

10

Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells.

Qian Y, Khattak SF, Xing Z, He A, Kayne PS, Qian NX, Pan SH, Li ZJ. Qian Y, et al. Among authors: qian nx. Biotechnol Prog. 2011 Jul;27(4):1190-4. doi: 10.1002/btpr.630. Epub 2011 May 18. Biotechnol Prog. 2011. PMID: 21595052

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