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Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Sukhanova A, Gorin A, Serebriiskii IG, Gabitova L, Zheng H, Restifo D, Egleston BL, Cunningham D, Bagnyukova T, Liu H, Nikonova A, Adams GP, Zhou Y, Yang DH, Mehra R, Burtness B, Cai KQ, Klein-Szanto A, Kratz LE, Kelley RI, Weiner LM, Herman GE, Golemis EA, Astsaturov I. Sukhanova A, et al. Among authors: astsaturov i. Cancer Discov. 2013 Jan;3(1):96-111. doi: 10.1158/2159-8290.CD-12-0031. Epub 2012 Nov 2. Cancer Discov. 2013. PMID: 23125191 Free PMC article.
Selective Raf inhibition in cancer therapy.
Khazak V, Astsaturov I, Serebriiskii IG, Golemis EA. Khazak V, et al. Among authors: astsaturov i. Expert Opin Ther Targets. 2007 Dec;11(12):1587-609. doi: 10.1517/14728222.11.12.1587. Expert Opin Ther Targets. 2007. PMID: 18020980 Free PMC article. Review.
Mechanisms of tumor resistance to EGFR-targeted therapies.
Hopper-Borge EA, Nasto RE, Ratushny V, Weiner LM, Golemis EA, Astsaturov I. Hopper-Borge EA, et al. Among authors: astsaturov i. Expert Opin Ther Targets. 2009 Mar;13(3):339-62. doi: 10.1517/14712590902735795. Expert Opin Ther Targets. 2009. PMID: 19236156 Free PMC article. Review.
Targeting EGFR resistance networks in head and neck cancer.
Ratushny V, Astsaturov I, Burtness BA, Golemis EA, Silverman JS. Ratushny V, et al. Among authors: astsaturov i. Cell Signal. 2009 Aug;21(8):1255-68. doi: 10.1016/j.cellsig.2009.02.021. Epub 2009 Mar 1. Cell Signal. 2009. PMID: 19258037 Free PMC article. Review.
75 results