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Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models.
Spoerke JM, O'Brien C, Huw L, Koeppen H, Fridlyand J, Brachmann RK, Haverty PM, Pandita A, Mohan S, Sampath D, Friedman LS, Ross L, Hampton GM, Amler LC, Shames DS, Lackner MR. Spoerke JM, et al. Among authors: ross l. Clin Cancer Res. 2012 Dec 15;18(24):6771-83. doi: 10.1158/1078-0432.CCR-12-2347. Epub 2012 Nov 7. Clin Cancer Res. 2012. PMID: 23136191
GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway.
Wallin JJ, Edgar KA, Guan J, Berry M, Prior WW, Lee L, Lesnick JD, Lewis C, Nonomiya J, Pang J, Salphati L, Olivero AG, Sutherlin DP, O'Brien C, Spoerke JM, Patel S, Lensun L, Kassees R, Ross L, Lackner MR, Sampath D, Belvin M, Friedman LS. Wallin JJ, et al. Among authors: ross l. Mol Cancer Ther. 2011 Dec;10(12):2426-36. doi: 10.1158/1535-7163.MCT-11-0446. Epub 2011 Oct 13. Mol Cancer Ther. 2011. PMID: 21998291
Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.
Wang X, Blackaby W, Allen V, Chan GKY, Chang JH, Chiang PC, Diène C, Drummond J, Do S, Fan E, Harstad EB, Hodges A, Hu H, Jia W, Kofie W, Kolesnikov A, Lyssikatos JP, Ly J, Matteucci M, Moffat JG, Munugalavadla V, Murray J, Nash D, Noland CL, Del Rosario G, Ross L, Rouse C, Sharpe A, Slaga D, Sun M, Tsui V, Wallweber H, Yu SF, Ebens AJ. Wang X, et al. Among authors: ross l. J Med Chem. 2019 Feb 28;62(4):2140-2153. doi: 10.1021/acs.jmedchem.8b01857. Epub 2019 Feb 20. J Med Chem. 2019. PMID: 30715878
The risk of high-biomass HABs: Triggers and dynamics of a non-toxic bloom of Prorocentrum micans in Chilean Patagonia.
Díaz PA, Basti L, Pérez-Santos I, Schwerter C, Artal O, Rosales SA, Ross L, Garreaud R, Conca C, Álvarez G, Fleming ZL, Villanueva F, Díaz M, Mancilla-Gutiérrez G, Altamirano R, Rodríguez-Villegas C, Urrutia P, Urrutia G, Linford P, Acuña-Ruz T, Figueroa RI. Díaz PA, et al. Among authors: ross l. Sci Total Environ. 2025 Jan 1;958:178140. doi: 10.1016/j.scitotenv.2024.178140. Epub 2024 Dec 18. Sci Total Environ. 2025. PMID: 39700974
The frequency and clinical associations of opioid use in systemic sclerosis.
Fairley JL, Hansen D, Proudman S, Sahhar J, Ngian GS, Apostolopoulos D, Walker J, Host LV, Stevens W, Ferdowsi N, Tabesh M, Nikpour M, Ross L. Fairley JL, et al. Among authors: ross l. Rheumatol Adv Pract. 2024 Nov 15;8(4):rkae144. doi: 10.1093/rap/rkae144. eCollection 2024. Rheumatol Adv Pract. 2024. PMID: 39669116 Free PMC article.
2,068 results