Fierke CA - Search Results

1

Recent advances in protein prenyltransferases: substrate identification, regulation, and disease interventions.

Zverina EA, Lamphear CL, Wright EN, Fierke CA. Zverina EA, et al. Among authors: fierke ca. Curr Opin Chem Biol. 2012 Dec;16(5-6):544-52. doi: 10.1016/j.cbpa.2012.10.015. Epub 2012 Nov 8. Curr Opin Chem Biol. 2012. PMID: 23141597 Free PMC article. Review.

2

Ribonuclease P: a ribonucleoprotein enzyme.

Kurz JC, Fierke CA. Kurz JC, et al. Among authors: fierke ca. Curr Opin Chem Biol. 2000 Oct;4(5):553-8. doi: 10.1016/s1367-5931(00)00131-9. Curr Opin Chem Biol. 2000. PMID: 11006544 Review.

3

A continuous fluorescent assay for protein prenyltransferases measuring diphosphate release.

Pais JE, Bowers KE, Stoddard AK, Fierke CA. Pais JE, et al. Among authors: fierke ca. Anal Biochem. 2005 Oct 15;345(2):302-11. doi: 10.1016/j.ab.2005.07.040. Anal Biochem. 2005. PMID: 16143290

4

Peptide specificity of protein prenyltransferases is determined mainly by reactivity rather than binding affinity.

Hartman HL, Hicks KA, Fierke CA. Hartman HL, et al. Among authors: fierke ca. Biochemistry. 2005 Nov 22;44(46):15314-24. doi: 10.1021/bi0509503. Biochemistry. 2005. PMID: 16285735

5

Context-dependent substrate recognition by protein farnesyltransferase.

Hougland JL, Lamphear CL, Scott SA, Gibbs RA, Fierke CA. Hougland JL, et al. Among authors: fierke ca. Biochemistry. 2009 Mar 3;48(8):1691-701. doi: 10.1021/bi801710g. Biochemistry. 2009. PMID: 19199818 Free PMC article.

6

Identification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivities.

Hougland JL, Hicks KA, Hartman HL, Kelly RA, Watt TJ, Fierke CA. Hougland JL, et al. Among authors: fierke ca. J Mol Biol. 2010 Jan 8;395(1):176-90. doi: 10.1016/j.jmb.2009.10.038. Epub 2009 Oct 28. J Mol Biol. 2010. PMID: 19878682 Free PMC article.

7

Identification of a novel class of farnesylation targets by structure-based modeling of binding specificity.

London N, Lamphear CL, Hougland JL, Fierke CA, Schueler-Furman O. London N, et al. Among authors: fierke ca. PLoS Comput Biol. 2011 Oct;7(10):e1002170. doi: 10.1371/journal.pcbi.1002170. Epub 2011 Oct 6. PLoS Comput Biol. 2011. PMID: 21998565 Free PMC article.

8

Mixed inhibition of adenosine deaminase activity by 1,3-dinitrobenzene: a model for understanding cell-selective neurotoxicity in chemically-induced energy deprivation syndromes in brain.

Wang Y, Liu X, Schneider B, Zverina EA, Russ K, Wijeyesakere SJ, Fierke CA, Richardson RJ, Philbert MA. Wang Y, et al. Among authors: fierke ca. Toxicol Sci. 2012 Feb;125(2):509-21. doi: 10.1093/toxsci/kfr317. Epub 2011 Nov 21. Toxicol Sci. 2012. PMID: 22106038 Free PMC article.

9

Discovering RNA-protein interactome by using chemical context profiling of the RNA-protein interface.

Parisien M, Wang X, Perdrizet G 2nd, Lamphear C, Fierke CA, Maheshwari KC, Wilde MJ, Sosnick TR, Pan T. Parisien M, et al. Among authors: fierke ca. Cell Rep. 2013 May 30;3(5):1703-13. doi: 10.1016/j.celrep.2013.04.010. Epub 2013 May 9. Cell Rep. 2013. PMID: 23665222 Free PMC article.

10

Exploration of GGTase-I substrate requirements. Part 1: Synthesis and biochemical evaluation of novel aryl-modified geranylgeranyl diphosphate analogs.

Temple KJ, Wright EN, Fierke CA, Gibbs RA. Temple KJ, et al. Among authors: fierke ca. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3499-502. doi: 10.1016/j.bmcl.2016.06.034. Epub 2016 Jun 16. Bioorg Med Chem Lett. 2016. PMID: 27342750 Free PMC article.

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