Pezzuto JM - Search Results

1

Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1).

Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Mayhoub AS, et al. Among authors: pezzuto jm. Bioorg Med Chem. 2012 Dec 15;20(24):7030-9. doi: 10.1016/j.bmc.2012.10.006. Epub 2012 Oct 23. Bioorg Med Chem. 2012. PMID: 23142320 Free PMC article.

2

Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis.

Maiti A, Cuendet M, Kondratyuk T, Croy VL, Pezzuto JM, Cushman M. Maiti A, et al. Among authors: pezzuto jm. J Med Chem. 2007 Jan 25;50(2):350-5. doi: 10.1021/jm060915+. J Med Chem. 2007. PMID: 17228877 Free PMC article.

3

Synthesis and biological evaluation of (+/-)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer.

Maiti A, Cuendet M, Croy VL, Endringer DC, Pezzuto JM, Cushman M. Maiti A, et al. Among authors: pezzuto jm. J Med Chem. 2007 Jun 14;50(12):2799-806. doi: 10.1021/jm070109i. Epub 2007 May 19. J Med Chem. 2007. PMID: 17511439

4

Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities.

Maiti A, Reddy PV, Sturdy M, Marler L, Pegan SD, Mesecar AD, Pezzuto JM, Cushman M. Maiti A, et al. Among authors: pezzuto jm. J Med Chem. 2009 Apr 9;52(7):1873-84. doi: 10.1021/jm801335z. J Med Chem. 2009. PMID: 19265439 Free PMC article.

5

Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites.

Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Hoshino J, et al. Among authors: pezzuto jm. J Med Chem. 2010 Jul 8;53(13):5033-43. doi: 10.1021/jm100274c. J Med Chem. 2010. PMID: 20527891 Free PMC article.

6

Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer.

Sun B, Hoshino J, Jermihov K, Marler L, Pezzuto JM, Mesecar AD, Cushman M. Sun B, et al. Among authors: pezzuto jm. Bioorg Med Chem. 2010 Jul 15;18(14):5352-66. doi: 10.1016/j.bmc.2010.05.042. Epub 2010 May 24. Bioorg Med Chem. 2010. PMID: 20558073 Free PMC article.

7

Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284.

Conda-Sheridan M, Marler L, Park EJ, Kondratyuk TP, Jermihov K, Mesecar AD, Pezzuto JM, Asolkar RN, Fenical W, Cushman M. Conda-Sheridan M, et al. Among authors: pezzuto jm. J Med Chem. 2010 Dec 23;53(24):8688-99. doi: 10.1021/jm1011066. Epub 2010 Nov 24. J Med Chem. 2010. PMID: 21105712 Free PMC article.

8

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.

Shen L, Park EJ, Kondratyuk TP, Guendisch D, Marler L, Pezzuto JM, Wright AD, Sun D. Shen L, et al. Among authors: pezzuto jm. Bioorg Med Chem. 2011 Nov 1;19(21):6182-95. doi: 10.1016/j.bmc.2011.09.020. Epub 2011 Sep 16. Bioorg Med Chem. 2011. PMID: 21978950 Free PMC article.

9

Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets.

Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Mayhoub AS, et al. Among authors: pezzuto jm. Bioorg Med Chem. 2012 Jan 1;20(1):510-20. doi: 10.1016/j.bmc.2011.09.031. Epub 2011 Sep 25. Bioorg Med Chem. 2012. PMID: 22115839 Free PMC article.

10

Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol.

Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Mayhoub AS, et al. Among authors: pezzuto jm. Bioorg Med Chem. 2012 Apr 1;20(7):2427-34. doi: 10.1016/j.bmc.2012.01.047. Epub 2012 Feb 11. Bioorg Med Chem. 2012. PMID: 22386564

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