Lygerou Z - Search Results

1

Reduced Geminin levels promote cellular senescence.

Iliou MS, Kotantaki P, Karamitros D, Spella M, Taraviras S, Lygerou Z. Iliou MS, et al. Among authors: lygerou z. Mech Ageing Dev. 2013 Jan-Feb;134(1-2):10-23. doi: 10.1016/j.mad.2012.10.001. Epub 2012 Nov 8. Mech Ageing Dev. 2013. PMID: 23142824

2

Cell cycle. License withheld--geminin blocks DNA replication.

Lygerou Z, Nurse P. Lygerou Z, et al. Science. 2000 Dec 22;290(5500):2271-3. doi: 10.1126/science.290.5500.2271. Science. 2000. PMID: 11188727

3

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase.

Nishitani H, Taraviras S, Lygerou Z, Nishimoto T. Nishitani H, et al. Among authors: lygerou z. J Biol Chem. 2001 Nov 30;276(48):44905-11. doi: 10.1074/jbc.M105406200. Epub 2001 Sep 12. J Biol Chem. 2001. PMID: 11555648 Free article.

4

Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines.

Xouri G, Lygerou Z, Nishitani H, Pachnis V, Nurse P, Taraviras S. Xouri G, et al. Among authors: lygerou z. Eur J Biochem. 2004 Aug;271(16):3368-78. doi: 10.1111/j.1432-1033.2004.04271.x. Eur J Biochem. 2004. PMID: 15291814 Free article.

5

Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1.

Karakaidos P, Taraviras S, Vassiliou LV, Zacharatos P, Kastrinakis NG, Kougiou D, Kouloukoussa M, Nishitani H, Papavassiliou AG, Lygerou Z, Gorgoulis VG. Karakaidos P, et al. Among authors: lygerou z. Am J Pathol. 2004 Oct;165(4):1351-65. doi: 10.1016/S0002-9440(10)63393-7. Am J Pathol. 2004. PMID: 15466399 Free PMC article.

6

Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma.

Roukos V, Iliou MS, Nishitani H, Gentzel M, Wilm M, Taraviras S, Lygerou Z. Roukos V, et al. Among authors: lygerou z. J Biol Chem. 2007 Mar 30;282(13):9346-9357. doi: 10.1074/jbc.M611643200. Epub 2007 Jan 29. J Biol Chem. 2007. PMID: 17261582 Free article.

7

Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin.

Xouri G, Squire A, Dimaki M, Geverts B, Verveer PJ, Taraviras S, Nishitani H, Houtsmuller AB, Bastiaens PI, Lygerou Z. Xouri G, et al. Among authors: lygerou z. EMBO J. 2007 Mar 7;26(5):1303-14. doi: 10.1038/sj.emboj.7601597. Epub 2007 Feb 22. EMBO J. 2007. PMID: 17318181 Free PMC article.

8

Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle.

Spella M, Britz O, Kotantaki P, Lygerou Z, Nishitani H, Ramsay RG, Flordellis C, Guillemot F, Mantamadiotis T, Taraviras S. Spella M, et al. Among authors: lygerou z. Neuroscience. 2007 Jun 29;147(2):373-87. doi: 10.1016/j.neuroscience.2007.03.050. Epub 2007 May 29. Neuroscience. 2007. PMID: 17533120

9

Cdt1 interactions in the licensing process: a model for dynamic spatiotemporal control of licensing.

Xouri G, Dimaki M, Bastiaens PI, Lygerou Z. Xouri G, et al. Among authors: lygerou z. Cell Cycle. 2007 Jul 1;6(13):1549-52. doi: 10.4161/cc.6.13.4455. Epub 2007 May 22. Cell Cycle. 2007. PMID: 17598984 Review.

10

Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior.

Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG. Liontos M, et al. Among authors: lygerou z. Cancer Res. 2007 Nov 15;67(22):10899-909. doi: 10.1158/0008-5472.CAN-07-2837. Cancer Res. 2007. PMID: 18006835

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