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Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA.
Richie TL, Charoenvit Y, Wang R, Epstein JE, Hedstrom RC, Kumar S, Luke TC, Freilich DA, Aguiar JC, Sacci JB Jr, Sedegah M, Nosek RA Jr, De La Vega P, Berzins MP, Majam VF, Abot EN, Ganeshan H, Richie NO, Banania JG, Baraceros MF, Geter TG, Mere R, Bebris L, Limbach K, Hickey BW, Lanar DE, Ng J, Shi M, Hobart PM, Norman JA, Soisson LA, Hollingdale MR, Rogers WO, Doolan DL, Hoffman SL. Richie TL, et al. Among authors: aguiar jc. Hum Vaccin Immunother. 2012 Nov 1;8(11):1564-84. doi: 10.4161/hv.22129. Epub 2012 Nov 1. Hum Vaccin Immunother. 2012. PMID: 23151451 Free PMC article. Clinical Trial.
Development of two monoclonal antibodies against Plasmodium falciparum sporozoite surface protein 2 and mapping of B-cell epitopes.
Charoenvit Y, Fallarme V, Rogers WO, Sacci JB Jr, Kaur M, Aguiar JC, Yuan LF, Corradin G, Andersen E, Wizel B, Houghten RA, Oloo A, De la Vega P, Hoffman SL. Charoenvit Y, et al. Among authors: aguiar jc. Infect Immun. 1997 Aug;65(8):3430-7. doi: 10.1128/iai.65.8.3430-3437.1997. Infect Immun. 1997. PMID: 9234808 Free PMC article.
86 results