Deinum J - Search Results

1

Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation.

Fjellström O, Deinum J, Sjögren T, Johansson C, Geschwindner S, Nerme V, Legnehed A, McPheat J, Olsson K, Bodin C, Paunovic A, Gustafsson D. Fjellström O, et al. Among authors: deinum j. J Biol Chem. 2013 Jan 11;288(2):873-85. doi: 10.1074/jbc.M112.371732. Epub 2012 Nov 15. J Biol Chem. 2013. PMID: 23155046 Free PMC article.

2

A serendipitously identified novel small molecule procoagulant compound giving rise to a high-throughput screening assay based on human plasma.

Gustafsson D, Nielsen S, McPheat J, Wågberg F, Kaspersson K, Rohman M, Ulander J, Fex T, Fjellström O, Deinum J. Gustafsson D, et al. Among authors: deinum j. Thromb Res. 2013 Aug;132(2):248-55. doi: 10.1016/j.thromres.2013.05.023. Epub 2013 Jul 3. Thromb Res. 2013. PMID: 23830061

3

Discovery of a novel warhead against beta-secretase through fragment-based lead generation.

Geschwindner S, Olsson LL, Albert JS, Deinum J, Edwards PD, de Beer T, Folmer RH. Geschwindner S, et al. Among authors: deinum j. J Med Chem. 2007 Nov 29;50(24):5903-11. doi: 10.1021/jm070825k. Epub 2007 Nov 7. J Med Chem. 2007. PMID: 17985861

4

Identification of structural-kinetic and structural-thermodynamic relationships for thrombin inhibitors.

Winquist J, Geschwindner S, Xue Y, Gustavsson L, Musil D, Deinum J, Danielson UH. Winquist J, et al. Among authors: deinum j. Biochemistry. 2013 Jan 29;52(4):613-26. doi: 10.1021/bi301333z. Epub 2013 Jan 16. Biochemistry. 2013. PMID: 23290007

5

The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis.

Elg M, Gustafsson D, Deinum J. Elg M, et al. Among authors: deinum j. Thromb Haemost. 1997 Oct;78(4):1286-92. Thromb Haemost. 1997. PMID: 9364999

6

A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization.

Egelund R, Einholm AP, Pedersen KE, Nielsen RW, Christensen A, Deinum J, Andreasen PA. Egelund R, et al. Among authors: deinum j. J Biol Chem. 2001 Apr 20;276(16):13077-86. doi: 10.1074/jbc.M009024200. Epub 2001 Jan 25. J Biol Chem. 2001. PMID: 11278457 Free article.

7

Effects of melagatran, a new low-molecular-weight thrombin inhibitor, on thrombin and fibrinolytic enzymes.

Gustafsson D, Antonsson T, Bylund R, Eriksson U, Gyzander E, Nilsson I, Elg M, Mattsson C, Deinum J, Pehrsson S, Karlsson O, Nilsson A, Sörensen H. Gustafsson D, et al. Among authors: deinum j. Thromb Haemost. 1998 Jan;79(1):110-8. Thromb Haemost. 1998. PMID: 9459334

8

Platelets retain high levels of active plasminogen activator inhibitor 1.

Brogren H, Wallmark K, Deinum J, Karlsson L, Jern S. Brogren H, et al. Among authors: deinum j. PLoS One. 2011;6(11):e26762. doi: 10.1371/journal.pone.0026762. Epub 2011 Nov 1. PLoS One. 2011. PMID: 22069469 Free PMC article.

9

A thermodynamic characterization of the binding of thrombin inhibitors to human thrombin, combining biosensor technology, stopped-flow spectrophotometry, and microcalorimetry.

Deinum J, Gustavsson L, Gyzander E, Kullman-Magnusson M, Edström A, Karlsson R. Deinum J, et al. Anal Biochem. 2002 Jan 15;300(2):152-62. doi: 10.1006/abio.2001.5454. Anal Biochem. 2002. PMID: 11779106

10

Biochemical and pharmacological effects of the direct thrombin inhibitor AR-H067637.

Deinum J, Mattsson C, Inghardt T, Elg M. Deinum J, et al. Thromb Haemost. 2009 Jun;101(6):1051-9. Thromb Haemost. 2009. PMID: 19492147

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

279 results

Search Page

Filters