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Combined immunophenotyping and fluorescence in situ hybridization with chromosome-specific DNA probes allows quantification and differentiation of ex vivo generated dendritic cells, leukemia-derived dendritic cells and clonal leukemic cells in patients with acute myeloid leukemia.
Kremser A, Kufner S, Konhaeuser E, Kroell T, Hausmann A, Tischer J, Kolb HJ, Zitzelsberger H, Schmetzer H. Kremser A, et al. Leuk Lymphoma. 2013 Jun;54(6):1297-308. doi: 10.3109/10428194.2012.751490. Epub 2012 Dec 26. Leuk Lymphoma. 2013. PMID: 23163701
The quality and quantity of leukemia-derived dendritic cells from patients with acute myeloid leukemia and myelodysplastic syndrome are a predictive factor for the lytic potential of dendritic cells-primed leukemia-specific T cells.
Grabrucker C, Liepert A, Dreyig J, Kremser A, Kroell T, Freudenreich M, Schmid C, Schweiger C, Tischer J, Kolb HJ, Schmetzer H. Grabrucker C, et al. Among authors: kremser a. J Immunother. 2010 Jun;33(5):523-37. doi: 10.1097/CJI.0b013e3181d87ffd. J Immunother. 2010. PMID: 20463595
Quality of T-cells after stimulation with leukemia-derived dendritic cells (DC) from patients with acute myeloid leukemia (AML) or myeloid dysplastic syndrome (MDS) is predictive for their leukemia cytotoxic potential.
Liepert A, Grabrucker C, Kremser A, Dreyssig J, Ansprenger C, Freudenreich M, Kroell T, Reibke R, Tischer J, Schweiger C, Schmid C, Kolb HJ, Schmetzer H. Liepert A, et al. Among authors: kremser a. Cell Immunol. 2010;265(1):23-30. doi: 10.1016/j.cellimm.2010.06.009. Epub 2010 Jun 20. Cell Immunol. 2010. PMID: 20663492
Cytokine Release Patterns in Mixed Lymphocyte Culture (MLC) of T-Cells with Dendritic Cells (DC) Generated from AML Blasts Contribute to Predict anti-Leukaemic T-Cell Reactions and Patients' Response to Immunotherapy.
Fischbacher D, Merle M, Liepert A, Grabrucker C, Kroell T, Kremser A, Dreyßig J, Freudenreich M, Schuster F, Borkhardt A, Kraemer D, Koehne CH, Kolb HJ, Schmid C, Schmetzer HM. Fischbacher D, et al. Among authors: kremser a. Cell Commun Adhes. 2015 Apr-Dec;22(2-6):49-65. doi: 10.1080/15419061.2016.1223634. Epub 2016 Sep 7. Cell Commun Adhes. 2015. PMID: 27602789 Free article.
Quantification of ex vivo generated dendritic cells (DC) and leukemia-derived DC contributes to estimate the quality of DC, to detect optimal DC-generating methods or to optimize DC-mediated T-cell-activation-procedures ex vivo or in vivo.
Schmetzer HM, Kremser A, Loibl J, Kroell T, Kolb HJ. Schmetzer HM, et al. Among authors: kremser a. Leukemia. 2007 Jun;21(6):1338-41. doi: 10.1038/sj.leu.2404639. Epub 2007 Mar 22. Leukemia. 2007. PMID: 17377593 No abstract available.
Serum Chemokine-release Profiles in AML-patients Might Contribute to Predict the Clinical Course of the Disease.
Merle M, Fischbacher D, Liepert A, Grabrucker C, Kroell T, Kremser A, Dreyssig J, Freudenreich M, Schuster F, Borkhardt A, Kraemer D, Koehne CH, Kolb HJ, Schmid C, Schmetzer HM. Merle M, et al. Among authors: kremser a. Immunol Invest. 2020 May;49(4):365-385. doi: 10.1080/08820139.2019.1661429. Epub 2019 Sep 19. Immunol Invest. 2020. PMID: 31535582
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