Goetz DH - Search Results

1

Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy.

Lee GM, Balouch E, Goetz DH, Lazic A, McKerrow JH, Craik CS. Lee GM, et al. Among authors: goetz dh. Biochemistry. 2012 Dec 18;51(50):10087-98. doi: 10.1021/bi301305k. Epub 2012 Dec 10. Biochemistry. 2012. PMID: 23181936 Free PMC article.

2

Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus.

Goetz DH, Choe Y, Hansell E, Chen YT, McDowell M, Jonsson CB, Roush WR, McKerrow J, Craik CS. Goetz DH, et al. Biochemistry. 2007 Jul 31;46(30):8744-52. doi: 10.1021/bi0621415. Epub 2007 Jul 3. Biochemistry. 2007. PMID: 17605471

3

Substrate modulation of enzyme activity in the herpesvirus protease family.

Lazic A, Goetz DH, Nomura AM, Marnett AB, Craik CS. Lazic A, et al. Among authors: goetz dh. J Mol Biol. 2007 Nov 2;373(4):913-23. doi: 10.1016/j.jmb.2007.07.073. Epub 2007 Aug 16. J Mol Biol. 2007. PMID: 17870089 Free PMC article.

4

A reverse binding motif that contributes to specific protease inhibition by antibodies.

Schneider EL, Lee MS, Baharuddin A, Goetz DH, Farady CJ, Ward M, Wang CI, Craik CS. Schneider EL, et al. Among authors: goetz dh. J Mol Biol. 2012 Jan 27;415(4):699-715. doi: 10.1016/j.jmb.2011.11.036. Epub 2011 Nov 27. J Mol Biol. 2012. PMID: 22154938 Free PMC article.

5

The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity.

Bell JK, Goetz DH, Mahrus S, Harris JL, Fletterick RJ, Craik CS. Bell JK, et al. Among authors: goetz dh. Nat Struct Biol. 2003 Jul;10(7):527-34. doi: 10.1038/nsb944. Nat Struct Biol. 2003. PMID: 12819769

6

Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii.

Mahon CS, O'Donoghue AJ, Goetz DH, Murray PG, Craik CS, Tuohy MG. Mahon CS, et al. Among authors: goetz dh. Microbiology (Reading). 2009 Nov;155(Pt 11):3673-3682. doi: 10.1099/mic.0.030940-0. Epub 2009 Jun 25. Microbiology (Reading). 2009. PMID: 19556294 Free PMC article.

7

Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.

Ohol YM, Goetz DH, Chan K, Shiloh MU, Craik CS, Cox JS. Ohol YM, et al. Among authors: goetz dh. Cell Host Microbe. 2010 Mar 18;7(3):210-20. doi: 10.1016/j.chom.2010.02.006. Cell Host Microbe. 2010. PMID: 20227664 Free PMC article.

8

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay.

Zhou Y, Agudelo J, Lu K, Goetz DH, Hansell E, Chen YT, Roush WR, McKerrow J, Craik CS, Amberg SM, Simmons G. Zhou Y, et al. Among authors: goetz dh. Antiviral Res. 2011 Nov;92(2):187-94. doi: 10.1016/j.antiviral.2011.07.016. Epub 2011 Jul 26. Antiviral Res. 2011. PMID: 21820471 Free PMC article.

9

Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration.

Duriseti S, Goetz DH, Hostetter DR, LeBeau AM, Wei Y, Craik CS. Duriseti S, et al. Among authors: goetz dh. J Biol Chem. 2010 Aug 27;285(35):26878-26888. doi: 10.1074/jbc.M109.077677. Epub 2010 May 25. J Biol Chem. 2010. PMID: 20501655 Free PMC article.

10

Inhibition of a secreted glutamic peptidase prevents growth of the fungus Talaromyces emersonii.

O'Donoghue AJ, Mahon CS, Goetz DH, O'Malley JM, Gallagher DM, Zhou M, Murray PG, Craik CS, Tuohy MG. O'Donoghue AJ, et al. Among authors: goetz dh. J Biol Chem. 2008 Oct 24;283(43):29186-95. doi: 10.1074/jbc.M802366200. Epub 2008 Aug 7. J Biol Chem. 2008. PMID: 18687686 Free PMC article.

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