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Minocycline blocks asthma-associated inflammation in part by interfering with the T cell receptor-nuclear factor κB-GATA-3-IL-4 axis without a prominent effect on poly(ADP-ribose) polymerase.
Naura AS, Kim H, Ju J, Rodriguez PC, Jordan J, Catling AD, Rezk BM, Abd Elmageed ZY, Pyakurel K, Tarhuni AF, Abughazleh MQ, Errami Y, Zerfaoui M, Ochoa AC, Boulares AH. Naura AS, et al. Among authors: kim h. J Biol Chem. 2013 Jan 18;288(3):1458-68. doi: 10.1074/jbc.M112.419580. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184953 Free PMC article.
Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy Antigen Receptor for Chemokines.
Zerfaoui M, Naura AS, Errami Y, Hans CP, Rezk BM, Park J, Elsegeiny W, Kim H, Lord K, Kim JG, Boulares AH. Zerfaoui M, et al. Among authors: kim h, kim jg. J Leukoc Biol. 2009 Dec;86(6):1385-92. doi: 10.1189/jlb.0309183. Epub 2009 Sep 10. J Leukoc Biol. 2009. PMID: 19741160 Free PMC article.
Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation.
Zerfaoui M, Errami Y, Naura AS, Suzuki Y, Kim H, Ju J, Liu T, Hans CP, Kim JG, Abd Elmageed ZY, Koochekpour S, Catling A, Boulares AH. Zerfaoui M, et al. Among authors: kim h, kim jg. J Immunol. 2010 Aug 1;185(3):1894-902. doi: 10.4049/jimmunol.1000646. Epub 2010 Jul 7. J Immunol. 2010. PMID: 20610652 Free PMC article.
Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment.
Ju J, Naura AS, Errami Y, Zerfaoui M, Kim H, Kim JG, Abd Elmageed ZY, Abdel-Mageed AB, Giardina C, Beg AA, Smulson ME, Boulares AH. Ju J, et al. Among authors: kim h, kim jg. J Biol Chem. 2010 Dec 24;285(52):41152-60. doi: 10.1074/jbc.M110.158352. Epub 2010 Oct 21. J Biol Chem. 2010. PMID: 20966071 Free PMC article.
Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonuclease that translocates to the nucleus during apoptosis.
Errami Y, Naura AS, Kim H, Ju J, Suzuki Y, El-Bahrawy AH, Ghonim MA, Hemeida RA, Mansy MS, Zhang J, Xu M, Smulson ME, Brim H, Boulares AH. Errami Y, et al. Among authors: kim h. J Biol Chem. 2013 Feb 1;288(5):3460-8. doi: 10.1074/jbc.M112.423061. Epub 2012 Dec 10. J Biol Chem. 2013. PMID: 23229555 Free PMC article.
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