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Minocycline blocks asthma-associated inflammation in part by interfering with the T cell receptor-nuclear factor κB-GATA-3-IL-4 axis without a prominent effect on poly(ADP-ribose) polymerase.
Naura AS, Kim H, Ju J, Rodriguez PC, Jordan J, Catling AD, Rezk BM, Abd Elmageed ZY, Pyakurel K, Tarhuni AF, Abughazleh MQ, Errami Y, Zerfaoui M, Ochoa AC, Boulares AH. Naura AS, et al. Among authors: zerfaoui m. J Biol Chem. 2013 Jan 18;288(3):1458-68. doi: 10.1074/jbc.M112.419580. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184953 Free PMC article.
Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content.
Hans CP, Zerfaoui M, Naura AS, Troxclair D, Strong JP, Matrougui K, Boulares AH. Hans CP, et al. Among authors: zerfaoui m. J Pharmacol Exp Ther. 2009 Apr;329(1):150-8. doi: 10.1124/jpet.108.145938. Epub 2009 Jan 5. J Pharmacol Exp Ther. 2009. PMID: 19124646 Free PMC article.
55 results