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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T. Narayan N, et al. Among authors: lombard d. Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Nature. 2012. Retraction in: Nature. 2014 Feb 27;506(7489):516. doi: 10.1038/nature12897 PMID: 23201684 Retracted.
SIRT6 in DNA repair, metabolism and ageing.
Lombard DB, Schwer B, Alt FW, Mostoslavsky R. Lombard DB, et al. J Intern Med. 2008 Feb;263(2):128-41. doi: 10.1111/j.1365-2796.2007.01902.x. J Intern Med. 2008. PMID: 18226091 Free PMC article.
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E. Hirschey MD, et al. Among authors: lombard db. Nature. 2010 Mar 4;464(7285):121-5. doi: 10.1038/nature08778. Nature. 2010. PMID: 20203611 Free PMC article.
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weissman S, Verdin E, Schwer B. Lombard DB, et al. Mol Cell Biol. 2007 Dec;27(24):8807-14. doi: 10.1128/MCB.01636-07. Epub 2007 Oct 8. Mol Cell Biol. 2007. PMID: 17923681 Free PMC article.
138 results