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Page 1
Development of a homogeneous high-throughput screening assay for biological inhibitors of human rhinovirus infection.
Newton P, O'Shea D, Wells E, Moakes K, Dunmore R, Butler RJ, Wilkinson T, Ward A, Casson N, Strain M, Vousden K, Lowe DC, Pattison DV, Carruthers AM, Sleeman MA, Vaughan TJ, Harrison P. Newton P, et al. Among authors: carruthers am. J Biomol Screen. 2013 Mar;18(3):237-46. doi: 10.1177/1087057112469047. Epub 2012 Dec 3. J Biomol Screen. 2013. PMID: 23207740
An anti-human ICAM-1 antibody inhibits rhinovirus-induced exacerbations of lung inflammation.
Traub S, Nikonova A, Carruthers A, Dunmore R, Vousden KA, Gogsadze L, Hao W, Zhu Q, Bernard K, Zhu J, Dymond M, McLean GR, Walton RP, Glanville N, Humbles A, Khaitov M, Wells T, Kolbeck R, Leishman AJ, Sleeman MA, Bartlett NW, Johnston SL. Traub S, et al. PLoS Pathog. 2013;9(8):e1003520. doi: 10.1371/journal.ppat.1003520. Epub 2013 Aug 1. PLoS Pathog. 2013. PMID: 23935498 Free PMC article.
Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Vousden KA, Lundqvist T, Popovic B, Naiman B, Carruthers AM, Newton P, Johnson DJD, Pomowski A, Wilkinson T, Dufner P, de Mendez I, Mallinder PR, Murray C, Strain M, Connor J, Murray LA, Sleeman MA, Lowe DC, Huntington JA, Vaughan TJ. Vousden KA, et al. Among authors: carruthers am. Sci Rep. 2019 Feb 7;9(1):1605. doi: 10.1038/s41598-019-38842-x. Sci Rep. 2019. PMID: 30733557 Free PMC article.
The TGF-β inhibitory activity of antibody 37E1B5 depends on its H-CDR2 glycan.
Tsui P, Higazi DR, Wu Y, Dunmore R, Solier E, Kasali T, Bond NJ, Huntington C, Carruthers A, Hood J, Borrok MJ, Barnes A, Rickert K, Phipps S, Shirinian L, Zhu J, Bowen MA, Dall'Acqua W, Murray LA. Tsui P, et al. MAbs. 2017 Jan;9(1):104-113. doi: 10.1080/19420862.2016.1255390. Epub 2016 Nov 11. MAbs. 2017. PMID: 27834568 Free PMC article.
FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis.
Leslie J, Millar BJ, Del Carpio Pons A, Burgoyne RA, Frost JD, Barksby BS, Luli S, Scott J, Simpson AJ, Gauldie J, Murray LA, Finch DK, Carruthers AM, Ferguson J, Sleeman MA, Rider D, Howarth R, Fox C, Oakley F, Fisher AJ, Mann DA, Borthwick LA. Leslie J, et al. Among authors: carruthers am. JCI Insight. 2020 Feb 27;5(4):e125937. doi: 10.1172/jci.insight.125937. JCI Insight. 2020. PMID: 32102985 Free PMC article.
Autoantibodies are associated with disease progression in idiopathic pulmonary fibrosis.
Koether K, Besnard V, Sandig H, Carruthers A, Miranda E, Grootenboer-Mignot S, Taillé C, Chevret S, Valeyre D, Nunes H, Israel-Biet D, Lim WK, Cottin V, Corkill D, Dobson C, Groves M, Ferraro F, Guenzi E, Huang L, Sulikowski M, Mailleux A, Murray LA, Mustelin T, Strickland I, Sleeman MA, Crestani B. Koether K, et al. Eur Respir J. 2023 May 18;61(5):2102381. doi: 10.1183/13993003.02381-2021. Print 2023 May. Eur Respir J. 2023. PMID: 37080573 Free article.
Divergent roles for Clusterin in Lung Injury and Repair.
Habiel DM, Camelo A, Espindola M, Burwell T, Hanna R, Miranda E, Carruthers A, Bell M, Coelho AL, Liu H, Pilataxi F, Clarke L, Grant E, Lewis A, Moore B, Knight DA, Hogaboam CM, Murray LA. Habiel DM, et al. Sci Rep. 2017 Nov 13;7(1):15444. doi: 10.1038/s41598-017-15670-5. Sci Rep. 2017. PMID: 29133960 Free PMC article.
Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF.
Monkley S, Overed-Sayer C, Parfrey H, Rassl D, Crowther D, Escudero-Ibarz L, Davis N, Carruthers A, Berks R, Coetzee M, Kolosionek E, Karlsson M, Griffin LR, Clausen M, Belfield G, Hogaboam CM, Murray LA. Monkley S, et al. Sci Rep. 2021 Nov 3;11(1):21584. doi: 10.1038/s41598-021-00769-7. Sci Rep. 2021. PMID: 34732748 Free PMC article.
24 results