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CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
McNerney ME, Brown CD, Wang X, Bartom ET, Karmakar S, Bandlamudi C, Yu S, Ko J, Sandall BP, Stricker T, Anastasi J, Grossman RL, Cunningham JM, Le Beau MM, White KP. McNerney ME, et al. Among authors: le beau mm. Blood. 2013 Feb 7;121(6):975-83. doi: 10.1182/blood-2012-04-426965. Epub 2012 Dec 3. Blood. 2013. PMID: 23212519 Free PMC article.
Haploinsufficiency of Apc leads to ineffective hematopoiesis.
Wang J, Fernald AA, Anastasi J, Le Beau MM, Qian Z. Wang J, et al. Among authors: le beau mm. Blood. 2010 Apr 29;115(17):3481-8. doi: 10.1182/blood-2009-11-251835. Epub 2010 Jan 11. Blood. 2010. PMID: 20065296 Free PMC article.
Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.
Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA. Vasanthakumar A, et al. Among authors: le beau mm. Blood. 2013 Mar 14;121(11):2059-63. doi: 10.1182/blood-2012-04-421065. Epub 2013 Jan 11. Blood. 2013. PMID: 23315164 Free PMC article.
An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.
Godley LA, Cunningham J, Dolan ME, Huang RS, Gurbuxani S, McNerney ME, Larson RA, Leong H, Lussier Y, Onel K, Odenike O, Stock W, White KP, Le Beau MM. Godley LA, et al. Among authors: le beau mm. Semin Oncol. 2011 Apr;38(2):215-24. doi: 10.1053/j.seminoncol.2011.01.003. Semin Oncol. 2011. PMID: 21421111 Free PMC article. Review.
Genetic pathways leading to therapy-related myeloid neoplasms.
Stoddart A, McNerney ME, Bartom E, Bergerson R, Young DJ, Qian Z, Wang J, Fernald AA, Davis EM, Larson RA, White KP, Le Beau MM. Stoddart A, et al. Among authors: le beau mm. Mediterr J Hematol Infect Dis. 2011;3(1):e2011019. doi: 10.4084/MJHID.2011.019. Epub 2011 May 16. Mediterr J Hematol Infect Dis. 2011. PMID: 21713073 Free PMC article.
483 results