Flatt PR - Search Results

1

Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice.

Gaudin-Audrain C, Irwin N, Mansur S, Flatt PR, Thorens B, Baslé M, Chappard D, Mabilleau G. Gaudin-Audrain C, et al. Among authors: flatt pr. Bone. 2013 Mar;53(1):221-30. doi: 10.1016/j.bone.2012.11.039. Epub 2012 Dec 6. Bone. 2013. PMID: 23220186 Free article.

2

DPP IV resistance and insulin releasing activity of a novel di-substituted analogue of glucose-dependent insulinotropic polypeptide, (Ser2-Asp13)GIP.

Gault VA, Irwin N, Harriott P, Flatt PR, O'Harte FP. Gault VA, et al. Among authors: flatt pr. Cell Biol Int. 2003;27(1):41-6. doi: 10.1016/s1065-6995(02)00255-x. Cell Biol Int. 2003. PMID: 12713798

3

Effects of short-term chemical ablation of the GIP receptor on insulin secretion, islet morphology and glucose homeostasis in mice.

Irwin N, Gault VA, Green BD, Greer B, McCluskey JT, Harriott P, O'Harte FP, Flatt PR. Irwin N, et al. Among authors: flatt pr. Biol Chem. 2004 Sep;385(9):845-52. doi: 10.1515/BC.2004.110. Biol Chem. 2004. PMID: 15493880

4

Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide.

Irwin N, Green BD, Gault VA, Greer B, Harriott P, Bailey CJ, Flatt PR, O'Harte FP. Irwin N, et al. Among authors: flatt pr. J Med Chem. 2005 Feb 24;48(4):1244-50. doi: 10.1021/jm049262s. J Med Chem. 2005. PMID: 15715491

5

A novel, long-acting agonist of glucose-dependent insulinotropic polypeptide suitable for once-daily administration in type 2 diabetes.

Irwin N, Green BD, Mooney MH, Greer B, Harriott P, Bailey CJ, Gault VA, O'Harte FP, Flatt PR. Irwin N, et al. Among authors: flatt pr. J Pharmacol Exp Ther. 2005 Sep;314(3):1187-94. doi: 10.1124/jpet.105.086082. Epub 2005 May 27. J Pharmacol Exp Ther. 2005. PMID: 15923344

6

Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3)GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes.

Gault VA, Irwin N, Green BD, McCluskey JT, Greer B, Bailey CJ, Harriott P, O'harte FP, Flatt PR. Gault VA, et al. Among authors: flatt pr. Diabetes. 2005 Aug;54(8):2436-46. doi: 10.2337/diabetes.54.8.2436. Diabetes. 2005. PMID: 16046312

7

Effects on glucose homeostasis and insulin secretion of long term activation of the glucose-dependent insulinotropic polypeptide (GIP) receptor by N-AcGIP(LysPAL37) in normal mice.

Irwin N, Green BD, Gault VA, Cassidy RS, O'Harte FP, Harriott P, Flatt PR. Irwin N, et al. Among authors: flatt pr. Peptides. 2006 Apr;27(4):893-900. doi: 10.1016/j.peptides.2005.08.003. Epub 2005 Sep 21. Peptides. 2006. PMID: 16181707

8

Antidiabetic potential of two novel fatty acid derivatised, N-terminally modified analogues of glucose-dependent insulinotropic polypeptide (GIP): N-AcGIP(LysPAL16) and N-AcGIP(LysPAL37).

Irwin N, Gault VA, Green BD, Greer B, Harriott P, Bailey CJ, Flatt PR, O'Harte FP. Irwin N, et al. Among authors: flatt pr. Biol Chem. 2005 Jul;386(7):679-87. doi: 10.1515/BC.2005.079. Biol Chem. 2005. PMID: 16207089

9

Stable agonist of glucose-dependent insulinotropic polypeptide (GIP) restores pancreatic beta cell glucose responsiveness but not glucose intolerance in aging mice.

Irwin N, Green BD, Gault VA, Harriot P, O'Harte FP, Flatt PR. Irwin N, et al. Among authors: flatt pr. Exp Gerontol. 2006 Feb;41(2):151-6. doi: 10.1016/j.exger.2005.11.006. Epub 2005 Dec 27. Exp Gerontol. 2006. PMID: 16378704

10

Pituitary adenylate cyclase-activating peptide (PACAP): assessment of dipeptidyl peptidase IV degradation, insulin-releasing activity and antidiabetic potential.

Green BD, Irwin N, Flatt PR. Green BD, et al. Among authors: flatt pr. Peptides. 2006 Jun;27(6):1349-58. doi: 10.1016/j.peptides.2005.11.010. Epub 2006 Jan 10. Peptides. 2006. PMID: 16406202

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