Druker BJ - Search Results

1

The selective SYK inhibitor P505-15 (PRT062607) inhibits B cell signaling and function in vitro and in vivo and augments the activity of fludarabine in chronic lymphocytic leukemia.

Spurgeon SE, Coffey G, Fletcher LB, Burke R, Tyner JW, Druker BJ, Betz A, DeGuzman F, Pak Y, Baker D, Pandey A, Hollenbach SJ, Sinha U, Loriaux MM. Spurgeon SE, et al. Among authors: druker bj. J Pharmacol Exp Ther. 2013 Feb;344(2):378-87. doi: 10.1124/jpet.112.200832. Epub 2012 Dec 7. J Pharmacol Exp Ther. 2013. PMID: 23220742 Free PMC article.

2

Recent advancements in the treatment of chronic myelogenous leukemia.

O'Dwyer ME, Mauro MJ, Druker BJ. O'Dwyer ME, et al. Among authors: druker bj. Annu Rev Med. 2002;53:369-81. doi: 10.1146/annurev.med.53.082901.103853. Annu Rev Med. 2002. PMID: 11818480 Review.

3

In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia.

La Rosée P, Johnson K, O'Dwyer ME, Druker BJ. La Rosée P, et al. Among authors: druker bj. Exp Hematol. 2002 Jul;30(7):729-37. doi: 10.1016/s0301-472x(02)00836-6. Exp Hematol. 2002. PMID: 12135670 Free article.

4

Practical management of patients with chronic myeloid leukemia receiving imatinib.

Deininger MW, O'Brien SG, Ford JM, Druker BJ. Deininger MW, et al. Among authors: druker bj. J Clin Oncol. 2003 Apr 15;21(8):1637-47. doi: 10.1200/JCO.2003.11.143. Epub 2003 Mar 13. J Clin Oncol. 2003. PMID: 12668652 Review.

5

Specific targeted therapy of chronic myelogenous leukemia with imatinib.

Deininger MW, Druker BJ. Deininger MW, et al. Among authors: druker bj. Pharmacol Rev. 2003 Sep;55(3):401-23. doi: 10.1124/pr.55.3.4. Epub 2003 Jul 17. Pharmacol Rev. 2003. PMID: 12869662 Review.

6

In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants.

O'Hare T, Walters DK, Stoffregen EP, Jia T, Manley PW, Mestan J, Cowan-Jacob SW, Lee FY, Heinrich MC, Deininger MW, Druker BJ. O'Hare T, et al. Among authors: druker bj. Cancer Res. 2005 Jun 1;65(11):4500-5. doi: 10.1158/0008-5472.CAN-05-0259. Cancer Res. 2005. PMID: 15930265

7

Establishment of a murine model of aggressive systemic mastocytosis/mast cell leukemia.

Demehri S, Corbin A, Loriaux M, Druker BJ, Deininger MW. Demehri S, et al. Among authors: druker bj. Exp Hematol. 2006 Mar;34(3):284-8. doi: 10.1016/j.exphem.2005.11.015. Exp Hematol. 2006. PMID: 16543062 Free article.

8

Activating alleles of JAK3 in acute megakaryoblastic leukemia.

Walters DK, Mercher T, Gu TL, O'Hare T, Tyner JW, Loriaux M, Goss VL, Lee KA, Eide CA, Wong MJ, Stoffregen EP, McGreevey L, Nardone J, Moore SA, Crispino J, Boggon TJ, Heinrich MC, Deininger MW, Polakiewicz RD, Gilliland DG, Druker BJ. Walters DK, et al. Among authors: druker bj. Cancer Cell. 2006 Jul;10(1):65-75. doi: 10.1016/j.ccr.2006.06.002. Cancer Cell. 2006. PMID: 16843266 Free article.

9

Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib.

La Rosée P, Jia T, Demehri S, Härtel N, de Vries P, Bonham L, Hollenback D, Singer JW, Melo JV, Druker BJ, Deininger MW. La Rosée P, et al. Among authors: druker bj. Clin Cancer Res. 2006 Nov 1;12(21):6540-6. doi: 10.1158/1078-0432.CCR-06-0140. Clin Cancer Res. 2006. PMID: 17085669

10

Characterization of murine JAK2V617F-positive myeloproliferative disease.

Bumm TG, Elsea C, Corbin AS, Loriaux M, Sherbenou D, Wood L, Deininger J, Silver RT, Druker BJ, Deininger MW. Bumm TG, et al. Among authors: druker bj. Cancer Res. 2006 Dec 1;66(23):11156-65. doi: 10.1158/0008-5472.CAN-06-2210. Cancer Res. 2006. PMID: 17145859

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