Chaussade C - Search Results

1

D-chiro-inositol attenuates epinephrine-stimulated hepatic glucose output in the isolated perfused liver independently of insulin.

Whiting L, Danaher RN, Ruggiero K, Lee CC, Chaussade C, Mulvey T, Phillips A, Loomes KM. Whiting L, et al. Among authors: chaussade c. Horm Metab Res. 2013 May;45(5):394-7. doi: 10.1055/s-0032-1330016. Epub 2012 Dec 7. Horm Metab Res. 2013. PMID: 23225249

2

Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat.

Smith GC, Chaussade C, Vickers M, Jensen J, Shepherd PR. Smith GC, et al. Among authors: chaussade c. Diabetologia. 2008 Dec;51(12):2309-17. doi: 10.1007/s00125-008-1152-3. Epub 2008 Oct 9. Diabetologia. 2008. PMID: 18843478

3

Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling.

Chaussade C, Rewcastle GW, Kendall JD, Denny WA, Cho K, Grønning LM, Chong ML, Anagnostou SH, Jackson SP, Daniele N, Shepherd PR. Chaussade C, et al. Biochem J. 2007 Jun 15;404(3):449-58. doi: 10.1042/BJ20070003. Biochem J. 2007. PMID: 17362206 Free PMC article.

4

Discovery of pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors.

Kendall JD, O'Connor PD, Marshall AJ, Frédérick R, Marshall ES, Lill CL, Lee WJ, Kolekar S, Chao M, Malik A, Yu S, Chaussade C, Buchanan C, Rewcastle GW, Baguley BC, Flanagan JU, Jamieson SM, Denny WA, Shepherd PR. Kendall JD, et al. Among authors: chaussade c. Bioorg Med Chem. 2012 Jan 1;20(1):69-85. doi: 10.1016/j.bmc.2011.11.029. Epub 2011 Nov 25. Bioorg Med Chem. 2012. PMID: 22177405

5

Both p110alpha and p110beta isoforms of phosphatidylinositol 3-OH-kinase are required for insulin signalling in the hypothalamus.

Tups A, Anderson GM, Rizwan M, Augustine RA, Chaussade C, Shepherd PR, Grattan DR. Tups A, et al. Among authors: chaussade c. J Neuroendocrinol. 2010 Jun;22(6):534-42. doi: 10.1111/j.1365-2826.2010.01975.x. Epub 2010 Mar 2. J Neuroendocrinol. 2010. PMID: 20236230

6

Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR.

Kendall JD, Giddens AC, Tsang KY, Frédérick R, Marshall ES, Singh R, Lill CL, Lee WJ, Kolekar S, Chao M, Malik A, Yu S, Chaussade C, Buchanan C, Rewcastle GW, Baguley BC, Flanagan JU, Jamieson SM, Denny WA, Shepherd PR. Kendall JD, et al. Among authors: chaussade c. Bioorg Med Chem. 2012 Jan 1;20(1):58-68. doi: 10.1016/j.bmc.2011.11.031. Epub 2011 Nov 25. Bioorg Med Chem. 2012. PMID: 22177407

7

Evidence for a role for the p110-alpha isoform of PI3K in skeletal function.

Grey A, Chaussade C, Empson V, Lin JM, Watson M, O'Sullivan S, Rewcastle G, Naot D, Cornish J, Shepherd P. Grey A, et al. Among authors: chaussade c. Biochem Biophys Res Commun. 2010 Jan 1;391(1):564-9. doi: 10.1016/j.bbrc.2009.11.099. Epub 2009 Nov 24. Biochem Biophys Res Commun. 2010. PMID: 19931507

8

Investigating the role of class-IA PI 3-kinase isoforms in adipocyte differentiation.

Kim JE, Shepherd PR, Chaussade C. Kim JE, et al. Among authors: chaussade c. Biochem Biophys Res Commun. 2009 Feb 20;379(4):830-4. doi: 10.1016/j.bbrc.2008.12.089. Epub 2008 Dec 27. Biochem Biophys Res Commun. 2009. PMID: 19114029

9

Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110alpha inhibitors.

Kendall JD, Rewcastle GW, Frederick R, Mawson C, Denny WA, Marshall ES, Baguley BC, Chaussade C, Jackson SP, Shepherd PR. Kendall JD, et al. Among authors: chaussade c. Bioorg Med Chem. 2007 Dec 15;15(24):7677-87. doi: 10.1016/j.bmc.2007.08.062. Epub 2007 Sep 4. Bioorg Med Chem. 2007. PMID: 17869522

10

Phosphoinositide-3-kinase (PI3K) inhibitors: identification of new scaffolds using virtual screening.

Frédérick R, Mawson C, Kendall JD, Chaussade C, Rewcastle GW, Shepherd PR, Denny WA. Frédérick R, et al. Among authors: chaussade c. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5842-7. doi: 10.1016/j.bmcl.2009.08.087. Epub 2009 Aug 29. Bioorg Med Chem Lett. 2009. PMID: 19748269

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