Sorensen PH - Search Results

1

IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors.

Evdokimova V, Tognon CE, Benatar T, Yang W, Krutikov K, Pollak M, Sorensen PH, Seth A. Evdokimova V, et al. Among authors: sorensen ph. Sci Signal. 2012 Dec 18;5(255):ra92. doi: 10.1126/scisignal.2003184. Sci Signal. 2012. PMID: 23250396

2

The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.

Tognon C, Garnett M, Kenward E, Kay R, Morrison K, Sorensen PH. Tognon C, et al. Among authors: sorensen ph. Cancer Res. 2001 Dec 15;61(24):8909-16. Cancer Res. 2001. PMID: 11751416

3

ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation.

Morrison KB, Tognon CE, Garnett MJ, Deal C, Sorensen PH. Morrison KB, et al. Among authors: sorensen ph. Oncogene. 2002 Aug 22;21(37):5684-95. doi: 10.1038/sj.onc.1205669. Oncogene. 2002. PMID: 12173038

4

A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

Lannon CL, Martin MJ, Tognon CE, Jin W, Kim SJ, Sorensen PH. Lannon CL, et al. Among authors: sorensen ph. J Biol Chem. 2004 Feb 20;279(8):6225-34. doi: 10.1074/jbc.M307388200. Epub 2003 Dec 9. J Biol Chem. 2004. PMID: 14668342 Free article.

5

Mutations in the SAM domain of the ETV6-NTRK3 chimeric tyrosine kinase block polymerization and transformation activity.

Tognon CE, Mackereth CD, Somasiri AM, McIntosh LP, Sorensen PH. Tognon CE, et al. Among authors: sorensen ph. Mol Cell Biol. 2004 Jun;24(11):4636-50. doi: 10.1128/MCB.24.11.4636-4650.2004. Mol Cell Biol. 2004. PMID: 15143160 Free PMC article.

6

Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney.

Anglesio MS, Evdokimova V, Melnyk N, Zhang L, Fernandez CV, Grundy PE, Leach S, Marra MA, Brooks-Wilson AR, Penninger J, Sorensen PH. Anglesio MS, et al. Among authors: sorensen ph. Hum Mol Genet. 2004 Sep 15;13(18):2061-74. doi: 10.1093/hmg/ddh215. Epub 2004 Jul 14. Hum Mol Genet. 2004. PMID: 15254018

7

Proteasome-mediated cleavage of the Y-box-binding protein 1 is linked to DNA-damage stress response.

Sorokin AV, Selyutina AA, Skabkin MA, Guryanov SG, Nazimov IV, Richard C, Th'ng J, Yau J, Sorensen PH, Ovchinnikov LP, Evdokimova V. Sorokin AV, et al. Among authors: sorensen ph. EMBO J. 2005 Oct 19;24(20):3602-12. doi: 10.1038/sj.emboj.7600830. Epub 2005 Sep 29. EMBO J. 2005. PMID: 16193061 Free PMC article.

8

The ETV6-NTRK3 chimeric tyrosine kinase suppresses TGF-beta signaling by inactivating the TGF-beta type II receptor.

Jin W, Kim BC, Tognon C, Lee HJ, Patel S, Lannon CL, Maris JM, Triche TJ, Sorensen PH, Kim SJ. Jin W, et al. Among authors: sorensen ph. Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16239-44. doi: 10.1073/pnas.0503137102. Epub 2005 Oct 28. Proc Natl Acad Sci U S A. 2005. PMID: 16258068 Free PMC article.

9

Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species.

Evdokimova V, Ruzanov P, Anglesio MS, Sorokin AV, Ovchinnikov LP, Buckley J, Triche TJ, Sonenberg N, Sorensen PH. Evdokimova V, et al. Among authors: sorensen ph. Mol Cell Biol. 2006 Jan;26(1):277-92. doi: 10.1128/MCB.26.1.277-292.2006. Mol Cell Biol. 2006. PMID: 16354698 Free PMC article.

10

Y-box binding protein 1: providing a new angle on translational regulation.

Evdokimova V, Ovchinnikov LP, Sorensen PH. Evdokimova V, et al. Among authors: sorensen ph. Cell Cycle. 2006 Jun;5(11):1143-7. doi: 10.4161/cc.5.11.2784. Epub 2006 Jun 1. Cell Cycle. 2006. PMID: 16721060 Review.

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