Bolze F - Search Results

1

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants.

Volckmar AL, Bolze F, Jarick I, Knoll N, Scherag A, Reinehr T, Illig T, Grallert H, Wichmann HE, Wiegand S, Biebermann H, Krude H, Fischer-Posovszky P, Rief W, Wabitsch M, Klingenspor M, Hebebrand J, Hinney A. Volckmar AL, et al. Among authors: bolze f. BMC Med Genomics. 2012 Dec 27;5:65. doi: 10.1186/1755-8794-5-65. BMC Med Genomics. 2012. PMID: 23270367 Free PMC article.

2

Rescue of melanocortin 4 receptor (MC4R) nonsense mutations by aminoglycoside-mediated read-through.

Brumm H, Mühlhaus J, Bolze F, Scherag S, Hinney A, Hebebrand J, Wiegand S, Klingenspor M, Grüters A, Krude H, Biebermann H. Brumm H, et al. Among authors: bolze f. Obesity (Silver Spring). 2012 May;20(5):1074-81. doi: 10.1038/oby.2011.202. Epub 2011 Jul 7. Obesity (Silver Spring). 2012. PMID: 21738238 Free article.

3

Aminoglycosides, but not PTC124 (Ataluren), rescue nonsense mutations in the leptin receptor and in luciferase reporter genes.

Bolze F, Mocek S, Zimmermann A, Klingenspor M. Bolze F, et al. Sci Rep. 2017 Apr 21;7(1):1020. doi: 10.1038/s41598-017-01093-9. Sci Rep. 2017. PMID: 28432296 Free PMC article.

4

Mouse models for the central melanocortin system.

Bolze F, Klingenspor M. Bolze F, et al. Genes Nutr. 2009 Jun;4(2):129-34. doi: 10.1007/s12263-009-0117-6. Epub 2009 Mar 6. Genes Nutr. 2009. PMID: 19266227 Free PMC article.

5

Evidence for Nr4a1 as a cold-induced effector of brown fat thermogenesis.

Kanzleiter T, Schneider T, Walter I, Bolze F, Eickhorst C, Heldmaier G, Klaus S, Klingenspor M. Kanzleiter T, et al. Among authors: bolze f. Physiol Genomics. 2005 Dec 14;24(1):37-44. doi: 10.1152/physiolgenomics.00204.2005. Epub 2005 Oct 11. Physiol Genomics. 2005. PMID: 16219868

6

Intrinsic differences in BRITE adipogenesis of primary adipocytes from two different mouse strains.

Li Y, Bolze F, Fromme T, Klingenspor M. Li Y, et al. Among authors: bolze f. Biochim Biophys Acta. 2014 Sep;1841(9):1345-52. doi: 10.1016/j.bbalip.2014.06.003. Epub 2014 Jun 19. Biochim Biophys Acta. 2014. PMID: 24953778

7

Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo.

Bolze F, Rink N, Brumm H, Kühn R, Mocek S, Schwarz AE, Kless C, Biebermann H, Wurst W, Rozman J, Klingenspor M. Bolze F, et al. Pharmacogenomics J. 2013 Feb;13(1):80-93. doi: 10.1038/tpj.2011.43. Epub 2011 Oct 4. Pharmacogenomics J. 2013. PMID: 21969101

8

PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy.

Morath V, Bolze F, Schlapschy M, Schneider S, Sedlmayer F, Seyfarth K, Klingenspor M, Skerra A. Morath V, et al. Among authors: bolze f. Mol Pharm. 2015 May 4;12(5):1431-42. doi: 10.1021/mp5007147. Epub 2015 Apr 10. Mol Pharm. 2015. PMID: 25811325 Free article.

9

Long-Acting PASylated Leptin Ameliorates Obesity by Promoting Satiety and Preventing Hypometabolism in Leptin-Deficient Lep(ob/ob) Mice.

Bolze F, Morath V, Bast A, Rink N, Schlapschy M, Mocek S, Skerra A, Klingenspor M. Bolze F, et al. Endocrinology. 2016 Jan;157(1):233-44. doi: 10.1210/en.2015-1519. Epub 2015 Oct 22. Endocrinology. 2016. PMID: 26492472

10

Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation.

Bolze F, Bast A, Mocek S, Morath V, Yuan D, Rink N, Schlapschy M, Zimmermann A, Heikenwalder M, Skerra A, Klingenspor M. Bolze F, et al. Diabetologia. 2016 Sep;59(9):2005-12. doi: 10.1007/s00125-016-4004-6. Epub 2016 Jun 7. Diabetologia. 2016. PMID: 27272237

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