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Page 1
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties.
Schwitalla S, Fingerle AA, Cammareri P, Nebelsiek T, Göktuna SI, Ziegler PK, Canli O, Heijmans J, Huels DJ, Moreaux G, Rupec RA, Gerhard M, Schmid R, Barker N, Clevers H, Lang R, Neumann J, Kirchner T, Taketo MM, van den Brink GR, Sansom OJ, Arkan MC, Greten FR. Schwitalla S, et al. Among authors: van den brink gr. Cell. 2013 Jan 17;152(1-2):25-38. doi: 10.1016/j.cell.2012.12.012. Epub 2012 Dec 27. Cell. 2013. PMID: 23273993 Free article.
Depletion of the colonic epithelial precursor cell compartment upon conditional activation of the hedgehog pathway.
van Dop WA, Uhmann A, Wijgerde M, Sleddens-Linkels E, Heijmans J, Offerhaus GJ, van den Bergh Weerman MA, Boeckxstaens GE, Hommes DW, Hardwick JC, Hahn H, van den Brink GR. van Dop WA, et al. Among authors: van den bergh weerman ma, van den brink gr. Gastroenterology. 2009 Jun;136(7):2195-2203.e1-7. doi: 10.1053/j.gastro.2009.02.068. Epub 2009 Mar 6. Gastroenterology. 2009. PMID: 19272384
Morphogens and the parietal cell: shaping up acid secretion.
Heijmans J, van den Brink GR. Heijmans J, et al. Among authors: van den brink gr. Gastroenterology. 2010 Dec;139(6):1830-3. doi: 10.1053/j.gastro.2010.10.035. Epub 2010 Oct 26. Gastroenterology. 2010. PMID: 21029799 No abstract available.
Role of mast cells in colorectal cancer development, the jury is still out.
Heijmans J, Büller NV, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: van den brink gr. Biochim Biophys Acta. 2012 Jan;1822(1):9-13. doi: 10.1016/j.bbadis.2010.12.001. Epub 2010 Dec 9. Biochim Biophys Acta. 2012. PMID: 21146606 Free article. Review.
Intestinal tumorigenesis is not affected by progesterone signaling in rodent models.
Heijmans J, Muncan V, Jacobs RJ, de Jonge-Muller ES, Graven L, Biemond I, Ederveen AG, Groothuis PG, Mosselman S, Hardwick JC, Hommes DW, van den Brink GR. Heijmans J, et al. Among authors: van den brink gr. PLoS One. 2011;6(7):e22620. doi: 10.1371/journal.pone.0022620. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818351 Free PMC article.
Rage mediated DAMP signaling in intestinal tumorigenesis.
Heijmans J, Büller NV, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: van den brink gr. Oncoimmunology. 2012 Oct 1;1(7):1165-1166. doi: 10.4161/onci.20929. Oncoimmunology. 2012. PMID: 23170266 Free PMC article.
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.
Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MC, van de Wetering M, Ferrante M, Lee AS, Onderwater JJ, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: van lidth de jeude jf, van den brink gr, van de wetering m. Cell Rep. 2013 Apr 25;3(4):1128-39. doi: 10.1016/j.celrep.2013.02.031. Epub 2013 Mar 28. Cell Rep. 2013. PMID: 23545496 Free article.
ER stress induces epithelial differentiation in the mouse oesophagus.
Rosekrans SL, Heijmans J, Büller NV, Westerlund J, Lee AS, Muncan V, van den Brink GR. Rosekrans SL, et al. Among authors: van den brink gr. Gut. 2015 Feb;64(2):195-202. doi: 10.1136/gutjnl-2013-306347. Epub 2014 Apr 30. Gut. 2015. PMID: 24789843
Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.
Büller NV, Rosekrans SL, Metcalfe C, Heijmans J, van Dop WA, Fessler E, Jansen M, Ahn C, Vermeulen JL, Westendorp BF, Robanus-Maandag EC, Offerhaus GJ, Medema JP, D'Haens GR, Wildenberg ME, de Sauvage FJ, Muncan V, van den Brink GR. Büller NV, et al. Among authors: van dop wa, van den brink gr. Gastroenterology. 2015 Jan;148(1):170-180.e6. doi: 10.1053/j.gastro.2014.10.006. Epub 2014 Oct 13. Gastroenterology. 2015. PMID: 25307863
163 results