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Preclinical antitumor activity of a nanoparticulate SN38.
Al-Kasspooles MF, Williamson SK, Henry D, Howell J, Niu F, Decedue CJ, Roby KF. Al-Kasspooles MF, et al. Among authors: roby kf. Invest New Drugs. 2013 Aug;31(4):871-80. doi: 10.1007/s10637-012-9919-2. Epub 2013 Jan 9. Invest New Drugs. 2013. PMID: 23299391
A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax®) in patients with peritoneal malignancies.
Williamson SK, Johnson GA, Maulhardt HA, Moore KM, McMeekin DS, Schulz TK, Reed GA, Roby KF, Mackay CB, Smith HJ, Weir SJ, Wick JA, Markman M, diZerega GS, Baltezor MJ, Espinosa J, Decedue CJ. Williamson SK, et al. Among authors: roby kf. Cancer Chemother Pharmacol. 2015 May;75(5):1075-87. doi: 10.1007/s00280-015-2737-4. Epub 2015 Apr 23. Cancer Chemother Pharmacol. 2015. PMID: 25898813 Free PMC article. Clinical Trial.
The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer.
Wilson C, Qiu L, Hong Y, Karnik T, Tadros G, Mau B, Ma T, Mu Y, New J, Louie RJ, Gunewardena S, Godwin AK, Tawfik OW, Chien J, Roby KF, Krieg AJ. Wilson C, et al. Among authors: roby kf. Oncogene. 2017 May 4;36(18):2565-2576. doi: 10.1038/onc.2016.412. Epub 2016 Nov 21. Oncogene. 2017. PMID: 27869162 Free PMC article.
Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer.
Gupta VG, Hirst J, Petersen S, Roby KF, Kusch M, Zhou H, Clive ML, Jewell A, Pathak HB, Godwin AK, Wilson AJ, Crispens MA, Cybulla E, Vindigni A, Fuh KC, Khabele D. Gupta VG, et al. Among authors: roby kf. Gynecol Oncol. 2021 Jul;162(1):163-172. doi: 10.1016/j.ygyno.2021.04.015. Epub 2021 Apr 16. Gynecol Oncol. 2021. PMID: 33867143 Free PMC article.
Selective targeting of IRAK1 attenuates low molecular weight hyaluronic acid-induced stemness and non-canonical STAT3 activation in epithelial ovarian cancer.
Standing D, Dandawate P, Gunewardena S, Covarrubias-Zambrano O, Roby KF, Khabele D, Jewell A, Tawfik O, Bossmann SH, Godwin AK, Weir SJ, Jensen RA, Anant S. Standing D, et al. Among authors: roby kf. Cell Death Dis. 2024 May 25;15(5):362. doi: 10.1038/s41419-024-06717-3. Cell Death Dis. 2024. PMID: 38796478 Free PMC article.
93 results