Gupta A - Search Results

1

Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases.

Zhu C, Gupta A, Hall VL, Rayla AL, Christensen RG, Dake B, Lakshmanan A, Kuperwasser C, Stormo GD, Wolfe SA. Zhu C, et al. Among authors: gupta a. Nucleic Acids Res. 2013 Feb 1;41(4):2455-65. doi: 10.1093/nar/gks1357. Epub 2013 Jan 8. Nucleic Acids Res. 2013. PMID: 23303772 Free PMC article.

2

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases.

Gupta A, Meng X, Zhu LJ, Lawson ND, Wolfe SA. Gupta A, et al. Nucleic Acids Res. 2011 Jan;39(1):381-92. doi: 10.1093/nar/gkq787. Epub 2010 Sep 14. Nucleic Acids Res. 2011. PMID: 20843781 Free PMC article.

3

An optimized two-finger archive for ZFN-mediated gene targeting.

Gupta A, Christensen RG, Rayla AL, Lakshmanan A, Stormo GD, Wolfe SA. Gupta A, et al. Nat Methods. 2012 Jun;9(6):588-90. doi: 10.1038/nmeth.1994. Epub 2012 Apr 29. Nat Methods. 2012. PMID: 22543349 Free PMC article.

4

Targeted chromosomal deletions and inversions in zebrafish.

Gupta A, Hall VL, Kok FO, Shin M, McNulty JC, Lawson ND, Wolfe SA. Gupta A, et al. Genome Res. 2013 Jun;23(6):1008-17. doi: 10.1101/gr.154070.112. Epub 2013 Mar 11. Genome Res. 2013. PMID: 23478401 Free PMC article.

5

Construction and application of site-specific artificial nucleases for targeted gene editing.

Kok FO, Gupta A, Lawson ND, Wolfe SA. Kok FO, et al. Among authors: gupta a. Methods Mol Biol. 2014;1101:267-303. doi: 10.1007/978-1-62703-721-1_13. Methods Mol Biol. 2014. PMID: 24233786

6

An improved predictive recognition model for Cys(2)-His(2) zinc finger proteins.

Gupta A, Christensen RG, Bell HA, Goodwin M, Patel RY, Pandey M, Enuameh MS, Rayla AL, Zhu C, Thibodeau-Beganny S, Brodsky MH, Joung JK, Wolfe SA, Stormo GD. Gupta A, et al. Nucleic Acids Res. 2014 Apr;42(8):4800-12. doi: 10.1093/nar/gku132. Epub 2014 Feb 12. Nucleic Acids Res. 2014. PMID: 24523353 Free PMC article.

7

A modified bacterial one-hybrid system yields improved quantitative models of transcription factor specificity.

Christensen RG, Gupta A, Zuo Z, Schriefer LA, Wolfe SA, Stormo GD. Christensen RG, et al. Among authors: gupta a. Nucleic Acids Res. 2011 Jul;39(12):e83. doi: 10.1093/nar/gkr239. Epub 2011 Apr 20. Nucleic Acids Res. 2011. PMID: 21507886 Free PMC article.

8

DNA-binding-domain fusions enhance the targeting range and precision of Cas9.

Bolukbasi MF, Gupta A, Oikemus S, Derr AG, Garber M, Brodsky MH, Zhu LJ, Wolfe SA. Bolukbasi MF, et al. Among authors: gupta a. Nat Methods. 2015 Dec;12(12):1150-6. doi: 10.1038/nmeth.3624. Epub 2015 Oct 19. Nat Methods. 2015. PMID: 26480473 Free PMC article.

9

GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases.

Zhu LJ, Lawrence M, Gupta A, Pagès H, Kucukural A, Garber M, Wolfe SA. Zhu LJ, et al. Among authors: gupta a. BMC Genomics. 2017 May 15;18(1):379. doi: 10.1186/s12864-017-3746-y. BMC Genomics. 2017. PMID: 28506212 Free PMC article.

10

Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.

Bolukbasi MF, Gupta A, Wolfe SA. Bolukbasi MF, et al. Among authors: gupta a. Nat Methods. 2016 Jan;13(1):41-50. doi: 10.1038/nmeth.3684. Nat Methods. 2016. PMID: 26716561 Review.

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