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Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism.
Slack E, Hapfelmeier S, Stecher B, Velykoredko Y, Stoel M, Lawson MA, Geuking MB, Beutler B, Tedder TF, Hardt WD, Bercik P, Verdu EF, McCoy KD, Macpherson AJ. Slack E, et al. Among authors: macpherson aj. Science. 2009 Jul 31;325(5940):617-20. doi: 10.1126/science.1172747. Science. 2009. PMID: 19644121 Free PMC article.
The maternal microbiota drives early postnatal innate immune development.
Gomez de Agüero M, Ganal-Vonarburg SC, Fuhrer T, Rupp S, Uchimura Y, Li H, Steinert A, Heikenwalder M, Hapfelmeier S, Sauer U, McCoy KD, Macpherson AJ. Gomez de Agüero M, et al. Among authors: macpherson aj. Science. 2016 Mar 18;351(6279):1296-302. doi: 10.1126/science.aad2571. Science. 2016. PMID: 26989247
Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy.
McCarthy DD, Kujawa J, Wilson C, Papandile A, Poreci U, Porfilio EA, Ward L, Lawson MA, Macpherson AJ, McCoy KD, Pei Y, Novak L, Lee JY, Julian BA, Novak J, Ranger A, Gommerman JL, Browning JL. McCarthy DD, et al. Among authors: macpherson aj. J Clin Invest. 2011 Oct;121(10):3991-4002. doi: 10.1172/JCI45563. Epub 2011 Sep 1. J Clin Invest. 2011. PMID: 21881212 Free PMC article.
The immune geography of IgA induction and function.
Macpherson AJ, McCoy KD, Johansen FE, Brandtzaeg P. Macpherson AJ, et al. Mucosal Immunol. 2008 Jan;1(1):11-22. doi: 10.1038/mi.2007.6. Mucosal Immunol. 2008. PMID: 19079156 Free article. Review.
248 results