Németh E - Search Results

1

The role of the N-terminal loop in the function of the colicin E7 nuclease domain.

Czene A, Németh E, Zóka IG, Jakab-Simon NI, Körtvélyesi T, Nagata K, Christensen HE, Gyurcsik B. Czene A, et al. Among authors: nemeth e. J Biol Inorg Chem. 2013 Mar;18(3):309-21. doi: 10.1007/s00775-013-0975-7. Epub 2013 Jan 19. J Biol Inorg Chem. 2013. PMID: 23334162 Free article.

2

Fine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N-terminal mutations.

Németh E, Körtvélyesi T, Thulstrup PW, Christensen HE, Kožíšek M, Nagata K, Czene A, Gyurcsik B. Németh E, et al. Protein Sci. 2014 Aug;23(8):1113-22. doi: 10.1002/pro.2497. Epub 2014 Jun 17. Protein Sci. 2014. PMID: 24895333 Free PMC article.

3

Design of a colicin E7 based chimeric zinc-finger nuclease.

Németh E, Schilli GK, Nagy G, Hasenhindl C, Gyurcsik B, Oostenbrink C. Németh E, et al. J Comput Aided Mol Des. 2014 Aug;28(8):841-50. doi: 10.1007/s10822-014-9765-8. Epub 2014 Jun 22. J Comput Aided Mol Des. 2014. PMID: 24952471 Free PMC article.

4

Substrate binding activates the designed triple mutant of the colicin E7 metallonuclease.

Németh E, Körtvélyesi T, Kožíšek M, Thulstrup PW, Christensen HE, Asaka MN, Nagata K, Gyurcsik B. Németh E, et al. J Biol Inorg Chem. 2014 Dec;19(8):1295-303. doi: 10.1007/s00775-014-1186-6. Epub 2014 Aug 26. J Biol Inorg Chem. 2014. PMID: 25156149

5

A new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational study.

Czene A, Tóth E, Németh E, Otten H, Poulsen JC, Christensen HE, Rulíšek L, Nagata K, Larsen S, Gyurcsik B. Czene A, et al. Among authors: nemeth e. Metallomics. 2014 Nov;6(11):2090-9. doi: 10.1039/c4mt00195h. Metallomics. 2014. PMID: 25179124

6

Preorganization of the catalytic Zn(2+)-binding site in the HNH nuclease motif--A solution study.

Németh E, Kožíšek M, Schilli GK, Gyurcsik B. Németh E, et al. J Inorg Biochem. 2015 Oct;151:143-9. doi: 10.1016/j.jinorgbio.2015.03.017. Epub 2015 Apr 9. J Inorg Biochem. 2015. PMID: 25898772

7

Intrinsic protein disorder could be overlooked in cocrystallization conditions: An SRCD case study.

Németh E, Balogh RK, Borsos K, Czene A, Thulstrup PW, Gyurcsik B. Németh E, et al. Protein Sci. 2016 Nov;25(11):1977-1988. doi: 10.1002/pro.3010. Epub 2016 Aug 23. Protein Sci. 2016. PMID: 27508941 Free PMC article.

8

Chemical Approach to Biological Safety: Molecular-Level Control of an Integrated Zinc Finger Nuclease.

Németh E, Asaka MN, Kato K, Fábián Z, Oostenbrink C, Christensen HEM, Nagata K, Gyurcsik B. Németh E, et al. Chembiochem. 2018 Jan 4;19(1):66-75. doi: 10.1002/cbic.201700420. Epub 2017 Dec 12. Chembiochem. 2018. PMID: 29077265

9

A study on the secondary structure of the metalloregulatory protein CueR: effect of pH, metal ions and DNA.

Balogh RK, Németh E, Jones NC, Hoffmann SV, Jancsó A, Gyurcsik B. Balogh RK, et al. Among authors: nemeth e. Eur Biophys J. 2021 May;50(3-4):491-500. doi: 10.1007/s00249-021-01539-z. Epub 2021 Apr 28. Eur Biophys J. 2021. PMID: 33907862

10

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents.

Póti Á, Gyergyák H, Németh E, Rusz O, Tóth S, Kovácsházi C, Chen D, Szikriszt B, Spisák S, Takeda S, Szakács G, Szallasi Z, Richardson AL, Szüts D. Póti Á, et al. Among authors: nemeth e. Genome Biol. 2019 Nov 14;20(1):240. doi: 10.1186/s13059-019-1867-0. Genome Biol. 2019. PMID: 31727117 Free PMC article.

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