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Page 1
Inactivation or loss of TTP promotes invasion in head and neck cancer via transcript stabilization and secretion of MMP9, MMP2, and IL-6.
Van Tubergen EA, Banerjee R, Liu M, Vander Broek R, Light E, Kuo S, Feinberg SE, Willis AL, Wolf G, Carey T, Bradford C, Prince M, Worden FP, Kirkwood KL, D'Silva NJ. Van Tubergen EA, et al. Among authors: vander broek r. Clin Cancer Res. 2013 Mar 1;19(5):1169-79. doi: 10.1158/1078-0432.CCR-12-2927. Epub 2013 Jan 24. Clin Cancer Res. 2013. PMID: 23349315 Free PMC article.
The G protein-coupled receptor GALR2 promotes angiogenesis in head and neck cancer.
Banerjee R, Van Tubergen EA, Scanlon CS, Vander Broek R, Lints JP, Liu M, Russo N, Inglehart RC, Wang Y, Polverini PJ, Kirkwood KL, D'Silva NJ. Banerjee R, et al. Among authors: vander broek r. Mol Cancer Ther. 2014 May;13(5):1323-33. doi: 10.1158/1535-7163.MCT-13-0904. Epub 2014 Feb 25. Mol Cancer Ther. 2014. PMID: 24568968 Free PMC article.
MEK Inhibitor PD-0325901 Overcomes Resistance to PI3K/mTOR Inhibitor PF-5212384 and Potentiates Antitumor Effects in Human Head and Neck Squamous Cell Carcinoma.
Mohan S, Vander Broek R, Shah S, Eytan DF, Pierce ML, Carlson SG, Coupar JF, Zhang J, Cheng H, Chen Z, Van Waes C. Mohan S, et al. Among authors: vander broek r. Clin Cancer Res. 2015 Sep 1;21(17):3946-56. doi: 10.1158/1078-0432.CCR-14-3377. Epub 2015 May 14. Clin Cancer Res. 2015. PMID: 25977343 Free PMC article.
PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.
Herzog A, Bian Y, Vander Broek R, Hall B, Coupar J, Cheng H, Sowers AL, Cook JD, Mitchell JB, Chen Z, Kulkarni AB, Van Waes C. Herzog A, et al. Among authors: vander broek r. Clin Cancer Res. 2013 Jul 15;19(14):3808-19. doi: 10.1158/1078-0432.CCR-12-2716. Epub 2013 May 2. Clin Cancer Res. 2013. PMID: 23640975 Free PMC article.
HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.
Friedman JA, Wise SC, Hu M, Gouveia C, Vander Broek R, Freudlsperger C, Kannabiran VR, Arun P, Mitchell JB, Chen Z, Van Waes C. Friedman JA, et al. Among authors: vander broek r. Transl Oncol. 2013 Aug 1;6(4):429-41. doi: 10.1593/tlo.13292. Print 2013 Aug. Transl Oncol. 2013. PMID: 23908686 Free PMC article.