Furlani RE - Search Results

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A flexible approach to 1,4-di-substituted 2-aminoimidazoles that inhibit and disperse biofilms and potentiate the effects of β-lactams against multi-drug resistant bacteria.

Furlani RE, Yeagley AA, Melander C. Furlani RE, et al. Eur J Med Chem. 2013 Apr;62:59-70. doi: 10.1016/j.ejmech.2012.12.005. Epub 2012 Dec 20. Eur J Med Chem. 2013. PMID: 23353733

Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives.

Richardson MA, Furlani RE, Podell BK, Ackart DF, Haugen JD, Melander RJ, Melander C, Basaraba RJ. Richardson MA, et al. Among authors: furlani re. Tetrahedron Lett. 2015;56(23):3406-3409. doi: 10.1016/j.tetlet.2015.01.122. Tetrahedron Lett. 2015. PMID: 26146419 Free PMC article.

Second generation 2-aminoimidazole based advanced glycation end product inhibitors and breakers.

Furlani RE, Richardson MA, Podell BK, Ackart DF, Haugen JD, Melander RJ, Basaraba RJ, Melander C. Furlani RE, et al. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4820-4823. doi: 10.1016/j.bmcl.2015.06.080. Epub 2015 Jun 29. Bioorg Med Chem Lett. 2015. PMID: 26187705 Free PMC article.

Second Generation Modifiers of Colistin Resistance Show Enhanced Activity and Lower Inherent Toxicity.

Brackett CM, Furlani RE, Anderson RG, Krishnamurthy A, Melander RJ, Moskowitz SM, Ernst RK, Melander C. Brackett CM, et al. Among authors: furlani re. Tetrahedron. 2016 Jun 23;72(25):3549-3553. doi: 10.1016/j.tet.2015.09.019. Tetrahedron. 2016. PMID: 27429479 Free PMC article.

Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator.

Liu C, Zhang H, Peng X, Blackledge MS, Furlani RE, Li H, Su Z, Melander RJ, Melander C, Michalek S, Wu H. Liu C, et al. Among authors: furlani re. mBio. 2023 Jun 27;14(3):e0013723. doi: 10.1128/mbio.00137-23. Epub 2023 Apr 19. mBio. 2023. PMID: 37074183 Free PMC article.

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