Peters SC - Search Results

1

Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulator.

Hao J, Dehlinger V, Fivush AM, Rudyk HC, Britton TC, Hollinshead SP, Vokits BP, Clark BP, Henry SS, Massey SM, Peng L, Dressman BA, Heinz BA, Roberts EF, Bracey-Walker MR, Swanson S, Catlow JT, Love PL, Tepool AD, Peters SC, Simmons RM, Iyengar S, McKinzie DL, Monn JA. Hao J, et al. Among authors: peters sc. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1249-52. doi: 10.1016/j.bmcl.2013.01.009. Epub 2013 Jan 12. Bioorg Med Chem Lett. 2013. PMID: 23374867

2

3-Phenyl-5-isothiazole carboxamides with potent mGluR1 antagonist activity.

Fisher MJ, Backer RT, Barth VN, Garbison KE, Gruber JM, Heinz BA, Iyengar S, Hollinshead SP, Kingston A, Kuklish SL, Li L, Nisenbaum ES, Peters SC, Phebus L, Simmons RM, van der Aar E. Fisher MJ, et al. Among authors: peters sc. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2514-7. doi: 10.1016/j.bmcl.2012.02.003. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22386665

3

Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing.

Jones CK, Eberle EL, Peters SC, Monn JA, Shannon HE. Jones CK, et al. Among authors: peters sc. Neuropharmacology. 2005;49 Suppl 1:206-18. doi: 10.1016/j.neuropharm.2005.05.008. Neuropharmacology. 2005. PMID: 15998527

4

Antihyperalgesic effects of the muscarinic receptor ligand vedaclidine in models involving central sensitization in rats.

Shannon HE, Jones CK, Li DL, Peters SC, Simmons RMA, Iyengar S. Shannon HE, et al. Among authors: peters sc. Pain. 2001 Sep;93(3):221-227. doi: 10.1016/S0304-3959(01)00319-0. Pain. 2001. PMID: 11514081

5

SAR and biological evaluation of novel trans-3,4-dimethyl-4-arylpiperidine derivatives as opioid antagonists.

Díaz N, Benvenga M, Emmerson P, Favors R, Mangold M, McKinzie J, Patel N, Peters S, Quimby S, Shannon H, Siegel M, Statnick M, Thomas E, Woodland J, Surface P, Mitch C. Díaz N, et al. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3844-8. doi: 10.1016/j.bmcl.2005.05.123. Bioorg Med Chem Lett. 2005. PMID: 15993591

6

Muscarinic analgesics with potent and selective effects on the gastrointestinal tract: potential application for the treatment of irritable bowel syndrome.

Mitch CH, Brown TJ, Bymaster FP, Calligaro DO, Dieckman D, Merrit L, Peters SC, Quimby SJ, Shannon HE, Shipley LA, Ward JS, Hansen K, Olesen PH, Sauerberg P, Sheardown MJ, Swedberg MD, Suzdak P, Greenwood B. Mitch CH, et al. Among authors: peters sc. J Med Chem. 1997 Feb 14;40(4):538-46. doi: 10.1021/jm9602470. J Med Chem. 1997. PMID: 9046345

7

Functionally selective M1 muscarinic agonists. 3. Side chains and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles.

Ward JS, Merritt L, Calligaro DO, Bymaster FP, Shannon HE, Sawyer BD, Mitch CH, Deeter JB, Peters SC, Sheardown MJ, Olesen PH, Swedberg MD, Sauerberg P. Ward JS, et al. Among authors: peters sc. J Med Chem. 1995 Sep 1;38(18):3469-81. doi: 10.1021/jm00018a007. J Med Chem. 1995. PMID: 7658434

8

Comparison of the effect of glutamate receptor modulators in the 6 Hz and maximal electroshock seizure models.

Barton ME, Peters SC, Shannon HE. Barton ME, et al. Among authors: peters sc. Epilepsy Res. 2003 Sep;56(1):17-26. doi: 10.1016/j.eplepsyres.2003.08.001. Epilepsy Res. 2003. PMID: 14529950

9

Anticonvulsant effects of LY456236, a selective mGlu1 receptor antagonist.

Shannon HE, Peters SC, Kingston AE. Shannon HE, et al. Among authors: peters sc. Neuropharmacology. 2005;49 Suppl 1:188-95. doi: 10.1016/j.neuropharm.2005.05.010. Neuropharmacology. 2005. PMID: 16011839

10

Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.

Jones CK, Peters SC, Shannon HE. Jones CK, et al. Among authors: peters sc. J Pharmacol Exp Ther. 2005 Feb;312(2):726-32. doi: 10.1124/jpet.104.075960. Epub 2004 Oct 19. J Pharmacol Exp Ther. 2005. PMID: 15494550

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