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Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts.
Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL. Gilkes DM, et al. J Biol Chem. 2013 Apr 12;288(15):10819-29. doi: 10.1074/jbc.M112.442939. Epub 2013 Feb 19. J Biol Chem. 2013. Retraction in: J Biol Chem. 2023 Sep;299(9):105144. doi: 10.1016/j.jbc.2023.105144 PMID: 23423382 Free PMC article. Retracted.
Sirtuin-7 inhibits the activity of hypoxia-inducible factors.
Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL. Hubbi ME, et al. Among authors: gilkes dm. J Biol Chem. 2013 Jul 19;288(29):20768-20775. doi: 10.1074/jbc.M113.476903. Epub 2013 Jun 9. J Biol Chem. 2013. PMID: 23750001 Free PMC article.
81 results