Wu L - Search Results

1

Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis.

He R, Zeng LF, He Y, Wu L, Gunawan AM, Zhang ZY. He R, et al. Among authors: wu l. Chem Commun (Camb). 2013 Mar 11;49(20):2064-6. doi: 10.1039/c3cc38961h. Chem Commun (Camb). 2013. PMID: 23380872 Free PMC article.

2

Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors.

Liu S, Zeng LF, Wu L, Yu X, Xue T, Gunawan AM, Long YQ, Zhang ZY. Liu S, et al. Among authors: wu l. J Am Chem Soc. 2008 Dec 17;130(50):17075-84. doi: 10.1021/ja8068177. J Am Chem Soc. 2008. PMID: 19012396 Free PMC article.

3

Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor.

He R, Yu Z, He Y, Zeng LF, Xu J, Wu L, Gunawan AM, Wang L, Jiang ZX, Zhang ZY. He R, et al. Among authors: wu l. ChemMedChem. 2010 Dec 3;5(12):2051-6. doi: 10.1002/cmdc.201000348. ChemMedChem. 2010. PMID: 20957718 Free PMC article.

4

Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.

He Y, Xu J, Yu ZH, Gunawan AM, Wu L, Wang L, Zhang ZY. He Y, et al. Among authors: wu l. J Med Chem. 2013 Feb 14;56(3):832-42. doi: 10.1021/jm301781p. Epub 2013 Jan 25. J Med Chem. 2013. PMID: 23305444 Free PMC article.

5

A facile hydroxyindole carboxylic acid based focused library approach for potent and selective inhibitors of Mycobacterium protein tyrosine phosphatase B.

Zeng LF, Xu J, He Y, He R, Wu L, Gunawan AM, Zhang ZY. Zeng LF, et al. Among authors: wu l. ChemMedChem. 2013 Jun;8(6):904-8. doi: 10.1002/cmdc.201300115. Epub 2013 Apr 8. ChemMedChem. 2013. PMID: 23568546 Free PMC article.

6

A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.

He Y, Liu S, Menon A, Stanford S, Oppong E, Gunawan AM, Wu L, Wu DJ, Barrios AM, Bottini N, Cato AC, Zhang ZY. He Y, et al. Among authors: wu dj, wu l. J Med Chem. 2013 Jun 27;56(12):4990-5008. doi: 10.1021/jm400248c. Epub 2013 Jun 6. J Med Chem. 2013. PMID: 23713581 Free PMC article.

7

Hydroxyindole carboxylic acid-based inhibitors for receptor-type protein tyrosine protein phosphatase beta.

Zeng LF, Zhang RY, Bai Y, Wu L, Gunawan AM, Zhang ZY. Zeng LF, et al. Among authors: wu l. Antioxid Redox Signal. 2014 May 10;20(14):2130-40. doi: 10.1089/ars.2013.5463. Epub 2014 Feb 4. Antioxid Redox Signal. 2014. PMID: 24180557 Free PMC article.

8

Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis.

He R, Bai Y, Yu ZH, Wu L, Gunawan AM, Zhang ZY. He R, et al. Among authors: wu l. Medchemcomm. 2014 Oct;5(10):1496-1499. doi: 10.1039/C4MD00099D. Medchemcomm. 2014. PMID: 25505942 Free PMC article.

9

A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.

He Y, Guo X, Yu ZH, Wu L, Gunawan AM, Zhang Y, Dixon JE, Zhang ZY. He Y, et al. Among authors: wu l. Bioorg Med Chem. 2015 Jun 15;23(12):2798-809. doi: 10.1016/j.bmc.2015.03.066. Epub 2015 Mar 31. Bioorg Med Chem. 2015. PMID: 25907364 Free PMC article.

10

Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis.

He R, Yu ZH, Zhang RY, Wu L, Gunawan AM, Zhang ZY. He R, et al. Among authors: wu l. ACS Med Chem Lett. 2015 Nov 3;6(12):1231-5. doi: 10.1021/acsmedchemlett.5b00373. eCollection 2015 Dec 10. ACS Med Chem Lett. 2015. PMID: 26713110 Free PMC article.

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