Herbst JJ - Search Results

1

Characterization of efflux transporters involved in distribution and disposition of apixaban.

Zhang D, He K, Herbst JJ, Kolb J, Shou W, Wang L, Balimane PV, Han YH, Gan J, Frost CE, Humphreys WG. Zhang D, et al. Among authors: herbst jj. Drug Metab Dispos. 2013 Apr;41(4):827-35. doi: 10.1124/dmd.112.050260. Epub 2013 Feb 4. Drug Metab Dispos. 2013. PMID: 23382458

2

Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen.

Wagner AD, Kolb JM, Ozbal CC, Herbst JJ, Olah TV, Weller HN, Zvyaga TA, Shou WZ. Wagner AD, et al. Among authors: herbst jj. Rapid Commun Mass Spectrom. 2011 May 15;25(9):1231-40. doi: 10.1002/rcm.4984. Rapid Commun Mass Spectrom. 2011. PMID: 21488121

3

Approach to improve compound recovery in a high-throughput Caco-2 permeability assay supported by liquid chromatography-tandem mass spectrometry.

Cai X, Walker A, Cheng C, Paiva A, Li Y, Kolb J, Herbst J, Shou W, Weller H. Cai X, et al. J Pharm Sci. 2012 Aug;101(8):2755-62. doi: 10.1002/jps.23194. Epub 2012 May 18. J Pharm Sci. 2012. PMID: 22611052

4

Addition of Optimized Bovine Serum Albumin Level in a High-Throughput Caco-2 Assay Enabled Accurate Permeability Assessment for Lipophilic Compounds.

Cai X, Madari S, Walker A, Paiva A, Li Y, Herbst J, Shou W, Weller H. Cai X, et al. SLAS Discov. 2019 Aug;24(7):738-744. doi: 10.1177/2472555219848483. Epub 2019 May 10. SLAS Discov. 2019. PMID: 31076010 Free article.

5

Cassette incubation followed by bioanalysis using high-resolution MS for in vitro ADME screening assays.

Zhang J, Maloney J, Drexler DM, Cai X, Stewart J, Mayer C, Herbst J, Weller H, Shou WZ. Zhang J, et al. Bioanalysis. 2012 Mar;4(5):581-93. doi: 10.4155/bio.12.2. Bioanalysis. 2012. PMID: 22409555

6

A systematic evaluation of solubility enhancing excipients to enable the generation of permeability data for poorly soluble compounds in Caco-2 model.

Shah D, Paruchury S, Matta M, Chowan G, Subramanian M, Saxena A, Soars MG, Herbst J, Haskell R, Marathe P, Mandlekar S. Shah D, et al. Drug Metab Lett. 2014;8(2):109-18. doi: 10.2174/1872312808666141127113055. Drug Metab Lett. 2014. PMID: 25429513

7

An integrated bioanalytical platform for supporting high-throughput serum protein binding screening.

Zhang J, Shou WZ, Vath M, Kieltyka K, Maloney J, Elvebak L, Stewart J, Herbst J, Weller HN. Zhang J, et al. Rapid Commun Mass Spectrom. 2010 Dec 30;24(24):3593-601. doi: 10.1002/rcm.4817. Rapid Commun Mass Spectrom. 2010. PMID: 21080511

8

Use of cryopreserved transiently transfected cells in high-throughput pregnane X receptor transactivation assay.

Zhu Z, Puglisi J, Connors D, Stewart J, Herbst J, Marino A, Sinz M, O'Connell J, Banks M, Dickinson K, Cacace A. Zhu Z, et al. J Biomol Screen. 2007 Mar;12(2):248-54. doi: 10.1177/1087057106297828. Epub 2007 Jan 26. J Biomol Screen. 2007. PMID: 17259590

9

Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines.

Civiello RL, Han X, Beno BR, Chaturvedula PV, Herbst JJ, Xu C, Conway CM, Macor JE, Dubowchik GM. Civiello RL, et al. Among authors: herbst jj. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1229-32. doi: 10.1016/j.bmcl.2016.01.026. Epub 2016 Jan 16. Bioorg Med Chem Lett. 2016. PMID: 26832218

10

Labware additives identified to be selective monoamine oxidase-B inhibitors.

Stewart J, Drexler DM, Leet JE, McNaney CA, Herbst JJ. Stewart J, et al. Among authors: herbst jj. J Biomol Screen. 2014 Dec;19(10):1409-14. doi: 10.1177/1087057114551523. Epub 2014 Oct 8. J Biomol Screen. 2014. PMID: 25296658

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