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Tubular von Hippel-Lindau knockout protects against rhabdomyolysis-induced AKI.
Fähling M, Mathia S, Paliege A, Koesters R, Mrowka R, Peters H, Persson PB, Neumayer HH, Bachmann S, Rosenberger C. Fähling M, et al. Among authors: koesters r. J Am Soc Nephrol. 2013 Nov;24(11):1806-19. doi: 10.1681/ASN.2013030281. Epub 2013 Aug 22. J Am Soc Nephrol. 2013. PMID: 23970125 Free PMC article.
Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts.
Schietke RE, Hackenbeck T, Tran M, Günther R, Klanke B, Warnecke CL, Knaup KX, Shukla D, Rosenberger C, Koesters R, Bachmann S, Betz P, Schley G, Schödel J, Willam C, Winkler T, Amann K, Eckardt KU, Maxwell P, Wiesener MS. Schietke RE, et al. Among authors: koesters r. PLoS One. 2012;7(1):e31034. doi: 10.1371/journal.pone.0031034. Epub 2012 Jan 27. PLoS One. 2012. PMID: 22299048 Free PMC article.
Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.
Khamaisi M, Toukan H, Axelrod JH, Rosenberger C, Skarzinski G, Shina A, Meidan R, Koesters R, Rosen S, Walkinshaw G, Mimura I, Nangaku M, Heyman SN. Khamaisi M, et al. Among authors: koesters r. Kidney Int. 2015 Apr;87(4):761-70. doi: 10.1038/ki.2014.362. Epub 2014 Dec 3. Kidney Int. 2015. PMID: 25469848 Free article.
In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli.
Nechemia-Arbely Y, Khamaisi M, Rosenberger C, Koesters R, Shina A, Geva C, Shriki A, Klaus S, Rosen S, Rose-John S, Galun E, Axelrod JH, Heyman SN. Nechemia-Arbely Y, et al. Among authors: koesters r. Clin Exp Pharmacol Physiol. 2013 Apr;40(4):262-72. doi: 10.1111/1440-1681.12064. Clin Exp Pharmacol Physiol. 2013. PMID: 23384058
An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.
Traykova-Brauch M, Schönig K, Greiner O, Miloud T, Jauch A, Bode M, Felsher DW, Glick AB, Kwiatkowski DJ, Bujard H, Horst J, von Knebel Doeberitz M, Niggli FK, Kriz W, Gröne HJ, Koesters R. Traykova-Brauch M, et al. Among authors: koesters r. Nat Med. 2008 Sep;14(9):979-84. doi: 10.1038/nm.1865. Nat Med. 2008. PMID: 18724376 Free PMC article.
Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease.
Hakroush S, Moeller MJ, Theilig F, Kaissling B, Sijmonsma TP, Jugold M, Akeson AL, Traykova-Brauch M, Hosser H, Hähnel B, Gröne HJ, Koesters R, Kriz W. Hakroush S, et al. Among authors: koesters r. Am J Pathol. 2009 Nov;175(5):1883-95. doi: 10.2353/ajpath.2009.080792. Epub 2009 Oct 15. Am J Pathol. 2009. PMID: 19834063 Free PMC article.
48 results