Darrah PA - Search Results

1

Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization.

Quinn KM, Da Costa A, Yamamoto A, Berry D, Lindsay RW, Darrah PA, Wang L, Cheng C, Kong WP, Gall JG, Nicosia A, Folgori A, Colloca S, Cortese R, Gostick E, Price DA, Gomez CE, Esteban M, Wyatt LS, Moss B, Morgan C, Roederer M, Bailer RT, Nabel GJ, Koup RA, Seder RA. Quinn KM, et al. Among authors: darrah pa. J Immunol. 2013 Mar 15;190(6):2720-35. doi: 10.4049/jimmunol.1202861. Epub 2013 Feb 6. J Immunol. 2013. PMID: 23390298 Free PMC article.

2

Dendritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in mice.

Shah JA, Darrah PA, Ambrozak DR, Turon TN, Mendez S, Kirman J, Wu CY, Glaichenhaus N, Seder RA. Shah JA, et al. Among authors: darrah pa. J Exp Med. 2003 Jul 21;198(2):281-91. doi: 10.1084/jem.20030645. J Exp Med. 2003. PMID: 12874261 Free PMC article.

3

Prime-boost vaccination with HIV-1 Gag protein and cytosine phosphate guanosine oligodeoxynucleotide, followed by adenovirus, induces sustained and robust humoral and cellular immune responses.

Tritel M, Stoddard AM, Flynn BJ, Darrah PA, Wu CY, Wille U, Shah JA, Huang Y, Xu L, Betts MR, Nabel GJ, Seder RA. Tritel M, et al. Among authors: darrah pa. J Immunol. 2003 Sep 1;171(5):2538-47. doi: 10.4049/jimmunol.171.5.2538. J Immunol. 2003. PMID: 12928404

4

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major.

Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, Flynn BJ, Hoff ST, Andersen P, Reed SG, Morris SL, Roederer M, Seder RA. Darrah PA, et al. Nat Med. 2007 Jul;13(7):843-50. doi: 10.1038/nm1592. Epub 2007 Jun 10. Nat Med. 2007. PMID: 17558415

5

T-cell quality in memory and protection: implications for vaccine design.

Seder RA, Darrah PA, Roederer M. Seder RA, et al. Among authors: darrah pa. Nat Rev Immunol. 2008 Apr;8(4):247-58. doi: 10.1038/nri2274. Epub 2008 Mar 7. Nat Rev Immunol. 2008. PMID: 18323851 Review.

6

Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells.

Lindenstrøm T, Agger EM, Korsholm KS, Darrah PA, Aagaard C, Seder RA, Rosenkrands I, Andersen P. Lindenstrøm T, et al. Among authors: darrah pa. J Immunol. 2009 Jun 15;182(12):8047-55. doi: 10.4049/jimmunol.0801592. J Immunol. 2009. PMID: 19494330

7

IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform.

Darrah PA, Hegde ST, Patel DT, Lindsay RW, Chen L, Roederer M, Seder RA. Darrah PA, et al. J Exp Med. 2010 Jul 5;207(7):1421-33. doi: 10.1084/jem.20092532. Epub 2010 Jun 7. J Exp Med. 2010. PMID: 20530206 Free PMC article.

8

CD8+ T cell responses following replication-defective adenovirus serotype 5 immunization are dependent on CD11c+ dendritic cells but show redundancy in their requirement of TLR and nucleotide-binding oligomerization domain-like receptor signaling.

Lindsay RW, Darrah PA, Quinn KM, Wille-Reece U, Mattei LM, Iwasaki A, Kasturi SP, Pulendran B, Gall JG, Spies AG, Seder RA. Lindsay RW, et al. Among authors: darrah pa. J Immunol. 2010 Aug 1;185(3):1513-21. doi: 10.4049/jimmunol.1000338. Epub 2010 Jul 7. J Immunol. 2010. PMID: 20610651

9

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.

Kastenmüller K, Wille-Reece U, Lindsay RW, Trager LR, Darrah PA, Flynn BJ, Becker MR, Udey MC, Clausen BE, Igyarto BZ, Kaplan DH, Kastenmüller W, Germain RN, Seder RA. Kastenmüller K, et al. Among authors: darrah pa. J Clin Invest. 2011 May;121(5):1782-96. doi: 10.1172/JCI45416. Epub 2011 Apr 11. J Clin Invest. 2011. PMID: 21540549 Free PMC article.

10

SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination.

Klatt NR, Vinton CL, Lynch RM, Canary LA, Ho J, Darrah PA, Estes JD, Seder RA, Moir SL, Brenchley JM. Klatt NR, et al. Among authors: darrah pa. Blood. 2011 Nov 24;118(22):5803-12. doi: 10.1182/blood-2011-07-365874. Epub 2011 Sep 29. Blood. 2011. PMID: 21960586 Free PMC article.

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