Siu V - Search Results

1

Nevirapine inhibits the anti-HIV activity of CD8+ cells.

Liu L, Wang L, Huang L, Siu V, Teque F, Aweeka FT, Levy JA. Liu L, et al. Among authors: siu v. J Acquir Immune Defic Syndr. 2013 Jun 1;63(2):184-8. doi: 10.1097/QAI.0b013e318289822d. J Acquir Immune Defic Syndr. 2013. PMID: 23392464 Free PMC article.

2

Development and validation of an oxygen dissociation assay, a screening platform for discovering, and characterizing hemoglobin-oxygen affinity modifiers.

Patel MP, Siu V, Silva-Garcia A, Xu Q, Li Z, Oksenberg D. Patel MP, et al. Among authors: siu v. Drug Des Devel Ther. 2018 Jun 1;12:1599-1607. doi: 10.2147/DDDT.S157570. eCollection 2018. Drug Des Devel Ther. 2018. PMID: 29910606 Free PMC article.

3

Pharmacokinetics and pharmacodynamics of voxelotor (GBT440) in healthy adults and patients with sickle cell disease.

Hutchaleelaha A, Patel M, Washington C, Siu V, Allen E, Oksenberg D, Gretler DD, Mant T, Lehrer-Graiwer J. Hutchaleelaha A, et al. Among authors: siu v. Br J Clin Pharmacol. 2019 Jun;85(6):1290-1302. doi: 10.1111/bcp.13896. Epub 2019 Mar 31. Br J Clin Pharmacol. 2019. PMID: 30743314 Free PMC article. Clinical Trial.

4

A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease.

Howard J, Hemmaway CJ, Telfer P, Layton DM, Porter J, Awogbade M, Mant T, Gretler DD, Dufu K, Hutchaleelaha A, Patel M, Siu V, Dixon S, Landsman N, Tonda M, Lehrer-Graiwer J. Howard J, et al. Among authors: siu v. Blood. 2019 Apr 25;133(17):1865-1875. doi: 10.1182/blood-2018-08-868893. Epub 2019 Jan 17. Blood. 2019. PMID: 30655275 Free PMC article. Clinical Trial.

5

GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model.

Dufu K, Alt C, Strutt S, Partridge J, Tang T, Siu V, Liao-Zou H, Rademacher P, Williams AT, Muller CR, Geng X, Pochron MP, Dang AN, Cabrales P, Li Z, Oksenberg D, Cathers BE. Dufu K, et al. Among authors: siu v. Br J Haematol. 2023 Jul;202(1):173-183. doi: 10.1111/bjh.18771. Epub 2023 Mar 24. Br J Haematol. 2023. PMID: 36960712

6

The search for pyruvate kinase-R activators; from a HTS screening hit via an impurity to the discovery of a lead series.

Yu C, Setti LQ, Nilar S, Li Z, Yu M, Partridge J, Choy R, Siu V, Strutt S, Zang R, Rademacher P, Bahmanjah S, Myslovaty Y, Zancanella M. Yu C, et al. Among authors: siu v. Bioorg Med Chem Lett. 2024 Sep 15;110:129865. doi: 10.1016/j.bmcl.2024.129865. Epub 2024 Jun 29. Bioorg Med Chem Lett. 2024. PMID: 38950758

7

Transfer RNA and small molecule therapeutics for aminoacyl-tRNA synthetase diseases.

Samuels TN, Wu F, Mahmood M, Abuzaid WA, Sun N, Moresco A, Siu VM, O'Donoghue P, Heinemann IU. Samuels TN, et al. Among authors: siu vm. FEBS J. 2024 Dec 19. doi: 10.1111/febs.17361. Online ahead of print. FEBS J. 2024. PMID: 39702998 Review.

8

Characterization of a novel heterozygous variant in the histidyl-tRNA synthetase gene associated with Charcot-Marie-Tooth disease type 2W.

Wilhelm SDP, Moresco AA, Rivero AD, Siu VM, Heinemann IU. Wilhelm SDP, et al. Among authors: siu vm. IUBMB Life. 2024 Dec;76(12):1125-1138. doi: 10.1002/iub.2918. Epub 2024 Oct 1. IUBMB Life. 2024. PMID: 39352000 Free PMC article.

9

Circles.

Siu VM, Siu JM. Siu VM, et al. Am J Med Genet C Semin Med Genet. 2024 Nov;196(2-3):e32105. doi: 10.1002/ajmg.c.32105. Epub 2024 Aug 31. Am J Med Genet C Semin Med Genet. 2024. PMID: 39215585 No abstract available.

10

Genesis and genetics of a miracle.

Siu VM. Siu VM. Am J Med Genet C Semin Med Genet. 2024 Nov;196(2-3):e32102. doi: 10.1002/ajmg.c.32102. Epub 2024 Aug 20. Am J Med Genet C Semin Med Genet. 2024. PMID: 39162357 No abstract available.

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