Morioka Y - Search Results

1

Design, synthesis, and binding mode prediction of 2-pyridone-based selective CB2 receptor agonists.

Kusakabe K, Tada Y, Iso Y, Sakagami M, Morioka Y, Chomei N, Shinonome S, Kawamoto K, Takenaka H, Yasui K, Hamana H, Hanasaki K. Kusakabe K, et al. Among authors: morioka y. Bioorg Med Chem. 2013 Apr 1;21(7):2045-55. doi: 10.1016/j.bmc.2013.01.006. Epub 2013 Jan 16. Bioorg Med Chem. 2013. PMID: 23395112

2

Purified group X secretory phospholipase A(2) induced prominent release of arachidonic acid from human myeloid leukemia cells.

Hanasaki K, Ono T, Saiga A, Morioka Y, Ikeda M, Kawamoto K, Higashino K, Nakano K, Yamada K, Ishizaki J, Arita H. Hanasaki K, et al. Among authors: morioka y. J Biol Chem. 1999 Nov 26;274(48):34203-11. doi: 10.1074/jbc.274.48.34203. J Biol Chem. 1999. PMID: 10567392 Free article.

3

Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor.

Morioka Y, Saiga A, Yokota Y, Suzuki N, Ikeda M, Ono T, Nakano K, Fujii N, Ishizaki J, Arita H, Hanasaki K. Morioka Y, et al. Arch Biochem Biophys. 2000 Sep 1;381(1):31-42. doi: 10.1006/abbi.2000.1977. Arch Biochem Biophys. 2000. PMID: 11019817

4

Potential role of group X secretory phospholipase A(2) in cyclooxygenase-2-dependent PGE(2) formation during colon tumorigenesis.

Morioka Y, Ikeda M, Saiga A, Fujii N, Ishimoto Y, Arita H, Hanasaki K. Morioka Y, et al. FEBS Lett. 2000 Dec 29;487(2):262-6. doi: 10.1016/s0014-5793(00)02350-4. FEBS Lett. 2000. PMID: 11150521 Free article.

5

Group X secretory phospholipase A(2) induces potent productions of various lipid mediators in mouse peritoneal macrophages.

Saiga A, Morioka Y, Ono T, Nakano K, Ishimoto Y, Arita H, Hanasaki K. Saiga A, et al. Among authors: morioka y. Biochim Biophys Acta. 2001 Jan 15;1530(1):67-76. doi: 10.1016/s1388-1981(00)00167-0. Biochim Biophys Acta. 2001. PMID: 11341959

6

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 1: discovery of CB2 receptor selective compounds.

Kai H, Morioka Y, Murashi T, Morita K, Shinonome S, Nakazato H, Kawamoto K, Hanasaki K, Takahashi F, Mihara S, Arai T, Abe K, Okabe H, Baba T, Yoshikawa T, Takenaka H. Kai H, et al. Among authors: morioka y. Bioorg Med Chem Lett. 2007 Jul 15;17(14):4030-4. doi: 10.1016/j.bmcl.2007.04.093. Epub 2007 Apr 30. Bioorg Med Chem Lett. 2007. PMID: 17521907

7

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: orally bioavailable compounds.

Kai H, Morioka Y, Tomida M, Takahashi T, Hattori M, Hanasaki K, Koike K, Chiba H, Shinohara S, Kanemasa T, Iwamoto Y, Takahashi K, Yamaguchi Y, Baba T, Yoshikawa T, Takenaka H. Kai H, et al. Among authors: morioka y. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3925-9. doi: 10.1016/j.bmcl.2007.04.099. Epub 2007 May 3. Bioorg Med Chem Lett. 2007. PMID: 17531479

8

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 3: Synthesis and activity of isosteric analogs.

Kai H, Morioka Y, Koriyama Y, Okamoto K, Hasegawa Y, Hattori M, Koike K, Chiba H, Shinohara S, Iwamoto Y, Takahashi K, Tanimoto N. Kai H, et al. Among authors: morioka y. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6444-7. doi: 10.1016/j.bmcl.2008.10.070. Epub 2008 Oct 19. Bioorg Med Chem Lett. 2008. PMID: 18977140

9

Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent.

Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: morioka y. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2898-901. doi: 10.1016/j.bmcl.2012.02.050. Epub 2012 Feb 23. Bioorg Med Chem Lett. 2012. PMID: 22421019

10

CB 1/2 dual agonists with 3-carbamoyl 2-pyridone derivatives as antipruritics: reduction of CNS side effects by introducing polar functional groups.

Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: morioka y. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2894-7. doi: 10.1016/j.bmcl.2012.02.054. Epub 2012 Mar 3. Bioorg Med Chem Lett. 2012. PMID: 22437111

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