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Page 1
Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen.
Malito E, Faleri A, Lo Surdo P, Veggi D, Maruggi G, Grassi E, Cartocci E, Bertoldi I, Genovese A, Santini L, Romagnoli G, Borgogni E, Brier S, Lo Passo C, Domina M, Castellino F, Felici F, van der Veen S, Johnson S, Lea SM, Tang CM, Pizza M, Savino S, Norais N, Rappuoli R, Bottomley MJ, Masignani V. Malito E, et al. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3304-9. doi: 10.1073/pnas.1222845110. Epub 2013 Feb 8. Proc Natl Acad Sci U S A. 2013. PMID: 23396847 Free PMC article.
Rational design of a meningococcal antigen inducing broad protective immunity.
Scarselli M, Aricò B, Brunelli B, Savino S, Di Marcello F, Palumbo E, Veggi D, Ciucchi L, Cartocci E, Bottomley MJ, Malito E, Lo Surdo P, Comanducci M, Giuliani MM, Cantini F, Dragonetti S, Colaprico A, Doro F, Giannetti P, Pallaoro M, Brogioni B, Tontini M, Hilleringmann M, Nardi-Dei V, Banci L, Pizza M, Rappuoli R. Scarselli M, et al. Among authors: malito e. Sci Transl Med. 2011 Jul 13;3(91):91ra62. doi: 10.1126/scitranslmed.3002234. Sci Transl Med. 2011. PMID: 21753121
Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197.
Malito E, Bursulaya B, Chen C, Lo Surdo P, Picchianti M, Balducci E, Biancucci M, Brock A, Berti F, Bottomley MJ, Nissum M, Costantino P, Rappuoli R, Spraggon G. Malito E, et al. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5229-34. doi: 10.1073/pnas.1201964109. Epub 2012 Mar 19. Proc Natl Acad Sci U S A. 2012. PMID: 22431623 Free PMC article.
Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus.
Schluepen C, Malito E, Marongiu A, Schirle M, McWhinnie E, Lo Surdo P, Biancucci M, Falugi F, Nardi-Dei V, Marchi S, Fontana MR, Lombardi B, De Falco MG, Rinaudo CD, Spraggon G, Nissum M, Bagnoli F, Grandi G, Bottomley MJ, Liberatori S. Schluepen C, et al. Among authors: malito e. Biochem J. 2013 Nov 1;455(3):273-84. doi: 10.1042/BJ20130540. Biochem J. 2013. PMID: 23895222
Comparison of CRM197, diphtheria toxoid and tetanus toxoid as protein carriers for meningococcal glycoconjugate vaccines.
Tontini M, Berti F, Romano MR, Proietti D, Zambonelli C, Bottomley MJ, De Gregorio E, Del Giudice G, Rappuoli R, Costantino P; Study Group; Brogioni G, Balocchi C, Biancucci M, Malito E. Tontini M, et al. Among authors: malito e. Vaccine. 2013 Oct 1;31(42):4827-33. doi: 10.1016/j.vaccine.2013.07.078. Epub 2013 Aug 17. Vaccine. 2013. PMID: 23965218
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of SpyCEP, a candidate antigen for a vaccine against Streptococcus pyogenes.
Abate F, Malito E, Falugi F, Margarit Y Ros I, Bottomley MJ. Abate F, et al. Among authors: malito e. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Oct;69(Pt 10):1103-6. doi: 10.1107/S1744309113024871. Epub 2013 Sep 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 24100558 Free PMC article.
Finding epitopes with computers.
Malito E, Rappuoli R. Malito E, et al. Chem Biol. 2013 Oct 24;20(10):1205-6. doi: 10.1016/j.chembiol.2013.10.002. Chem Biol. 2013. PMID: 24210005
46 results